Coronalolide
Modify Date: 2024-01-20 20:35:25
Coronalolide structure
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Common Name | Coronalolide | ||
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| CAS Number | 268214-51-3 | Molecular Weight | 482.651 | |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 646.3±20.0 °C at 760 mmHg | |
| Molecular Formula | C30H42O5 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 208.2±15.3 °C | |
Use of CoronalolideCoronalolide is a natural triterpene with anticancer effects. Coronalolide exhibits a broad cytotoxic activity for human breast (BT474), gastric (KATO-3), lung (CHAGO), colon (SW-620), and liver (Hep-G2) cancer cell lines, with IC50 values of 6.59 µg/mL, 5.85 µg/mL, 5.42 µg/mL, 4.98 µg/mL, and 6.41 µg/mL, respectively[1]. |
| Name | 3-((1aS,3aR,4R,6aS,6bS,7aR,10aR,10bR)-3a,6a-dimethyl-4-((R,E)-6-methyl-7-oxohept-5-en-2-yl)-10-methylene-9-oxododecahydro-1H-cyclopenta[7,8]cyclopropa[4,4a]naphtho[2,3-b]furan-10b(2H)-yl)propanoic acid |
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| Synonym | More Synonyms |
| Description | Coronalolide is a natural triterpene with anticancer effects. Coronalolide exhibits a broad cytotoxic activity for human breast (BT474), gastric (KATO-3), lung (CHAGO), colon (SW-620), and liver (Hep-G2) cancer cell lines, with IC50 values of 6.59 µg/mL, 5.85 µg/mL, 5.42 µg/mL, 4.98 µg/mL, and 6.41 µg/mL, respectively[1]. |
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| Related Catalog | |
| References |
| Density | 1.2±0.1 g/cm3 |
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| Boiling Point | 646.3±20.0 °C at 760 mmHg |
| Molecular Formula | C30H42O5 |
| Molecular Weight | 482.651 |
| Flash Point | 208.2±15.3 °C |
| Exact Mass | 482.303223 |
| PSA | 80.67000 |
| LogP | 5.95 |
| Vapour Pressure | 0.0±4.2 mmHg at 25°C |
| Index of Refraction | 1.562 |
| Hazard Codes | Xi |
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| 3-[(1aS,3aR,4R,6aS,6bS,7aR,10aR,10bR)-3a,6a-Dimethyl-10-methylene-4-[(2R,5E)-6-methyl-7-oxo-5-hepten-2-yl]-9-oxododecahydro-1H-cyclopenta[7,8]cyclopropa[4,4a]naphtho[2,3-b]furan-10b(2H)-yl]propanoic acid |
| 1H-Cyclopenta[7,8]cyclopropa[4,4a]naphtho[2,3-b]furan-10b(2H)-propanoic acid, 4-[(1R,4E)-1,5-dimethyl-6-oxo-4-hexen-1-yl]dodecahydro-3a,6a-dimethyl-10-methylene-9-oxo-, (1aS,3aR,4R,6aS,6bS,7aR,10aR,10bR)- |
| 1H-Cyclopenta[7,8]cyclopropa[4,4a]naphtho[2,3-b]furan-10b(2H)-propanoic acid, 4-[(1R,4E)-1,5-dimethyl-6-oxo-4-hexenyl]dodecahydro-3a,6a-dimethyl-10-methylene-9-oxo-, (1aS,3aR,4R,6aS,6bS,7aR,10aR,10bR) |