EBOV/MARV-IN-3

Modify Date: 2024-09-19 11:07:57

EBOV/MARV-IN-3 Structure
EBOV/MARV-IN-3 structure
Common Name EBOV/MARV-IN-3
CAS Number 2687245-05-0 Molecular Weight 534.52
Density N/A Boiling Point N/A
Molecular Formula C27H29F3N2O6 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of EBOV/MARV-IN-3


EBOV/MARV-IN-3 (compound 32) is a potent EBOV and MARV inhibitor with IC50 values of 0.5, 1.2 µM, respectively. EBOV/MARV-IN-3 binds to the hydrophobic pocket close to EBOV Y517. EBOV/MARV-IN-3 shows antiviral activity[1].

 Names

Name EBOV/MARV-IN-3

 EBOV/MARV-IN-3 Biological Activity

Description EBOV/MARV-IN-3 (compound 32) is a potent EBOV and MARV inhibitor with IC50 values of 0.5, 1.2 µM, respectively. EBOV/MARV-IN-3 binds to the hydrophobic pocket close to EBOV Y517. EBOV/MARV-IN-3 shows antiviral activity[1].
Related Catalog
Target

IC50: 0.5 µM (EBOV); 1.2 µM (MARV)[1]

References

[1]. Gao Y, et al. Development of coumarine derivatives as potent anti-filovirus entry inhibitors targeting viral glycoprotein. Eur J Med Chem. 2020 Oct 15;204:112595.  

 Chemical & Physical Properties

Molecular Formula C27H29F3N2O6
Molecular Weight 534.52