Trk-IN-10

Modify Date: 2024-01-09 21:37:02

Trk-IN-10 structure	Common Name	Trk-IN-10
	CAS Number	2700265-61-6	Molecular Weight	397.40
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₀H₂₀FN₅O₃	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Trk-IN-10

Trk-IN-10 (Compound 14j) is a potent inhibitor of TRK (IC50 = 0.86, 6.92 nM, against TrkA, TrkAG595R, respectively). As a receptor tyrosine kinase (RTK), tropomyosin receptor kinase (Trk) is a key drug target in solid tumors. Trk-IN-10 (IC50 = 350 nM against ALK) has a higher selectivity of Trk inhibition, which may be of great significance for reducing toxicity[1].

Name	Trk-IN-10

Description	Trk-IN-10 (Compound 14j) is a potent inhibitor of TRK (IC50 = 0.86, 6.92 nM, against TrkA, TrkAG595R, respectively). As a receptor tyrosine kinase (RTK), tropomyosin receptor kinase (Trk) is a key drug target in solid tumors. Trk-IN-10 (IC50 = 350 nM against ALK) has a higher selectivity of Trk inhibition, which may be of great significance for reducing toxicity[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Protein Tyrosine Kinase/RTK >> Trk Receptor
References	[1]. Fan Y, et al. Pyrizolo[1,5-a]pyrimidine derivatives of the second-generation TRK inhibitor: Design, synthesis and biological evaluation. Bioorg Med Chem Lett. 2022;63:128646.

Molecular Formula	C₂₀H₂₀FN₅O₃
Molecular Weight	397.40

DC Chemicals Limited
China
Product Name: Trk-IN-10
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Get all suppliers and price by the below link:

Trk-IN-10 suppliers

Trk-IN-10 price

Trk-IN-10

Use of Trk-IN-10

Names

Trk-IN-10 Biological Activity

Chemical & Physical Properties