N-(4-(2-benzimidazolyl)phenyl)maleimide

Modify Date: 2024-01-05 18:07:39

N-(4-(2-benzimidazolyl)phenyl)maleimide Structure
N-(4-(2-benzimidazolyl)phenyl)maleimide structure
Common Name N-(4-(2-benzimidazolyl)phenyl)maleimide
CAS Number 27030-97-3 Molecular Weight 289.288
Density 1.4±0.1 g/cm3 Boiling Point 556.3±52.0 °C at 760 mmHg
Molecular Formula C17H11N3O2 Melting Point 247ºC
MSDS N/A Flash Point 290.3±30.7 °C
Symbol GHS03 GHS05 GHS06 GHS08 GHS09
GHS03, GHS05, GHS06, GHS08, GHS09
Signal Word Danger

 Use of N-(4-(2-benzimidazolyl)phenyl)maleimide


N-[4-(2-Benzimidazolyl)phenyl]maleimide is a potent fluorescent probe with excitation maximum of 315 nm and emission maximum of 360 nm. N-[4-(2-Benzimidazolyl)phenyl]maleimide can be used for fluorometry of thiol compounds[1].

 Names

Name 1-[4-(1H-benzimidazol-2-yl)phenyl]pyrrole-2,5-dione
Synonym More Synonyms

 N-(4-(2-benzimidazolyl)phenyl)maleimide Biological Activity

Description N-[4-(2-Benzimidazolyl)phenyl]maleimide is a potent fluorescent probe with excitation maximum of 315 nm and emission maximum of 360 nm. N-[4-(2-Benzimidazolyl)phenyl]maleimide can be used for fluorometry of thiol compounds[1].
Related Catalog
References

[1]. Tanaka F, et, al. Determination of cysteine concentration by fluorescence increase: reaction of cysteine with a fluorogenic aldehyde. Chem Commun (Camb). 2004 Aug 7;(15):1762-3.

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 556.3±52.0 °C at 760 mmHg
Melting Point 247ºC
Molecular Formula C17H11N3O2
Molecular Weight 289.288
Flash Point 290.3±30.7 °C
Exact Mass 289.085114
PSA 66.06000
LogP 2.12
Vapour Pressure 0.0±1.5 mmHg at 25°C
Index of Refraction 1.742

 Safety Information

Symbol GHS03 GHS05 GHS06 GHS08 GHS09
GHS03, GHS05, GHS06, GHS08, GHS09
Signal Word Danger
Hazard Statements H272-H301-H312-H314-H317-H330-H334-H340-H350-H360FD-H372-H410
Precautionary Statements P201-P210-P260-P284-P301 + P310 + P330-P303 + P361 + P353-P304 + P340 + P310-P305 + P351 + P338-P308 + P313-P403 + P233
Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Safety Phrases S22-S24/25
RIDADR UN3086 - class 6.1 - PG 1 - PIH - RQ - Toxic solids, oxidizing, n.o.s., HI: all
RTECS HX7750000
HS Code 2933990090

 Customs

HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Articles19

More Articles
Conformational change accompanying formation of oligomycin-induced Na(+)-bound forms and their conversion to ADP-sensitive phosphoenzymes in Na+,K(+)-ATPase.

J. Biochem. 109(2) , 299-306, (1991)

Oligomycin reduced the fluorescence intensity of an N-(p-(2-benzimidazoly)phenyl) maleimide (BIPM) probe at Cys-964 of the alpha-chain of pig kidney Na+,K(+)-ATPase with increase in the concentration ...

Different susceptibility to phospholipase A2 treatment of the fluorescence intensity changes in the vicinity of Cys-964 and Lys-501 in the alpha-chain of probe-labeled Na+,K(+)-ATPase.

J. Biochem. 115(3) , 454-62, (1994)

Phospholipase A2 [EC 3.1.1.4] treatment of pig kidney Na+,K(+)-ATPase [EC 3.6.1.3] labeled with fluorescence probes at the alpha-chain reduced the extent of the fluorescence intensity change of an N-[...

ATP-induced dynamic fluorescence changes of a N-[p-(2-benzimidazolyl)phenyl]maleimide probe at Cys241 in the alpha-chain of pig stomach H+,K+-ATPase.

J. Biochem. 122(3) , 659-65, (1997)

H+,K+-ATPase preparations from pig stomach were modified with a sulfhydryl fluorescence reagent, N-[p-(2-benzimidazolyl)phenyl] maleimide (BIPM). The addition of ATP to the modified enzyme preparation...

 Synonyms

EINECS 248-173-3
N-[4-(2-benzimidazolyl)phenyl]-maleimide
1H-Pyrrole-2,5-dione, 1-[4-(1H-benzimidazol-2-yl)phenyl]-
N-[4-(1H-benzoimidazol-2-yl)-phenyl]-maleimide
1-[4-(1H-Benzimidazol-2-yl)phenyl]-1H-pyrrole-2,5-dione
MFCD00042767
BIPM
N-[p-(2-benzimidazolyl)phenyl]maleimide
N-<p-(2-Benzimidazolyl)phenyl>maleinimid
N-(4-(2-benzimidazolyl)phenyl)maleimide
N-[4-(2-Benzimidazolyl)phenyl]maleimide