LRRK2-IN-10

Modify Date: 2024-02-05 19:37:28

LRRK2-IN-10 structure	Common Name	LRRK2-IN-10
	CAS Number	2704562-80-9	Molecular Weight	341.37
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₀H₁₅N₅O	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of LRRK2-IN-10

LRRK2-IN-10 (compound 34) is a potent, mutation-selective, and brain penetrant G2019S-LRRK2 kinase inhibitor with IC50s of 11 nM and 5.2 nM for G2019S-LRRK2 pS935 and G2019S-LRRK2 pS1292, respectively. LRRK2-IN-10 has the potential for Parkinson's disease research[1].

Name	LRRK2-IN-10

Description	LRRK2-IN-10 (compound 34) is a potent, mutation-selective, and brain penetrant G2019S-LRRK2 kinase inhibitor with IC50s of 11 nM and 5.2 nM for G2019S-LRRK2 pS935 and G2019S-LRRK2 pS1292, respectively. LRRK2-IN-10 has the potential for Parkinson's disease research[1].
Related Catalog	Signaling Pathways >> Autophagy >> LRRK2 Research Areas >> Neurological Disease
References	[1]. Albert W Garofalo, et al. Brain-penetrant cyanoindane and cyanotetralin inhibitors of G2019S-LRRK2 kinase activity.

Molecular Formula	C₂₀H₁₅N₅O
Molecular Weight	341.37

LRRK2-IN-10

Use of LRRK2-IN-10

Names

LRRK2-IN-10 Biological Activity

Chemical & Physical Properties