DL-4-FluoroglutaMic acid

Modify Date: 2024-01-20 10:54:28

DL-4-FluoroglutaMic acid Structure
DL-4-FluoroglutaMic acid structure
Common Name DL-4-FluoroglutaMic acid
CAS Number 2708-77-2 Molecular Weight 165.12000
Density 1.498 g/cm3 Boiling Point 342.4ºC at 760 mmHg
Molecular Formula C5H8FNO4 Melting Point 185°C (dec.)
MSDS Chinese USA Flash Point 160.9ºC
Symbol GHS07
GHS07
Signal Word Warning

 Use of DL-4-FluoroglutaMic acid


4-Fluoro-DL-glutamic acid is a glutamic acid derivative[1].

 Names

Name 4-fluoro-dl-glutamic acid
Synonym More Synonyms

 DL-4-FluoroglutaMic acid Biological Activity

Description 4-Fluoro-DL-glutamic acid is a glutamic acid derivative[1].
Related Catalog
In Vitro Amino acids and amino acid derivatives have been commercially used as ergogenic supplements. They influence the secretion of anabolic hormones, supply of fuel during exercise, mental performance during stress related tasks and prevent exercise induced muscle damage. They are recognized to be beneficial as ergogenic dietary substances[1].
References

[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144.

 Chemical & Physical Properties

Density 1.498 g/cm3
Boiling Point 342.4ºC at 760 mmHg
Melting Point 185°C (dec.)
Molecular Formula C5H8FNO4
Molecular Weight 165.12000
Flash Point 160.9ºC
Exact Mass 165.04400
PSA 100.62000
Vapour Pressure 1.37E-05mmHg at 25°C
Index of Refraction 1.491

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi: Irritant;
Risk Phrases R36/37/38
Safety Phrases S26
RIDADR NONH for all modes of transport
WGK Germany 3
HS Code 2922499990

 Synthetic Route

~84%

DL-4-FluoroglutaMic acid Structure

DL-4-Fluoroglut...

CAS#:2708-77-2

Literature: Tolman, V.; Vlasakova, V.; Nemecek, J. Journal of Fluorine Chemistry, 1993 , vol. 60, # 2.3 p. 185 - 191

~81%

DL-4-FluoroglutaMic acid Structure

DL-4-Fluoroglut...

CAS#:2708-77-2

Literature: Tolman, V. Journal of Fluorine Chemistry, 1993 , vol. 60, # 2.3 p. 179 - 183

~%

DL-4-FluoroglutaMic acid Structure

DL-4-Fluoroglut...

CAS#:2708-77-2

Literature: Tolman,V.; Veres,K. Tetrahedron Letters, 1966 , p. 3909 - 3912

~%

DL-4-FluoroglutaMic acid Structure

DL-4-Fluoroglut...

CAS#:2708-77-2

Literature: Alekseewa,L.V. et al. J. Gen. Chem. USSR (Engl. Transl.), 1967 , vol. 37, p. 1754 - 1755,1671 - 1672

~%

DL-4-FluoroglutaMic acid Structure

DL-4-Fluoroglut...

CAS#:2708-77-2

Literature: Alekseewa,L.V. et al. J. Gen. Chem. USSR (Engl. Transl.), 1967 , vol. 37, p. 1754 - 1755,1671 - 1672

~%

DL-4-FluoroglutaMic acid Structure

DL-4-Fluoroglut...

CAS#:2708-77-2

Literature: Tolman,V.; Veres,K. Tetrahedron Letters, 1966 , p. 3909 - 3912

~%

DL-4-FluoroglutaMic acid Structure

DL-4-Fluoroglut...

CAS#:2708-77-2

Literature: Bergmann,E.D.; Chun-Hsu,L. Synthesis, 1973 , p. 44 - 46

 Customs

HS Code 2922499990
Summary HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%

 Articles11

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J. Med. Chem. 54(1) , 406-10, (2011)

There is a high demand for tumor specific PET tracers in oncology imaging. Besides glucose, certain amino acids also serve as energy sources and anabolic precursors for tumors. Therefore, (18)F-labele...

Mutations of the Corynebacterium glutamicum NCgl1221 gene, encoding a mechanosensitive channel homolog, induce L-glutamic acid production.

Appl. Environ. Microbiol. 73(14) , 4491-8, (2007)

Corynebacterium glutamicum is a biotin auxotroph that secretes L-glutamic acid in response to biotin limitation; this process is employed in industrial L-glutamic acid production. Fatty acid ester sur...

Vitamin K-dependent carboxylation. Study of the hydrogen abstraction stereochemistry with gamma-fluoroglutamic acid-containing peptides.

J. Biol. Chem. 258(13) , 7897-9, (1983)

Two pentapeptides Phe-Leu-X-Glu-Val where X is either the L-threo-gamma-fluoroglutamic acid or the L-erythro-isomer have been synthesized and tested as substrates in the vitamin K-dependent carboxylat...

 Synonyms

4-Fluoro-2-aminopentanedioic acid
2-Amino-4-fluoropentane-1,5-dioic acid
EINECS 220-302-8
4-Fluoro-Glutamic Acid
threo-4-fluoroglutamic acid
D,L-erythro,threo-4-fluoroglutamic acid
H-4-F-DL-Glu-OH
erythro-4-fluoroglutamic acid
DL-erythro-4-fluoroglutamic acid
DL-4-FLUOROGLUTAMIC ACID
MFCD00055778