Dimethylamino-PEG3

Modify Date: 2024-01-03 09:08:39

Dimethylamino-PEG3 Structure
Dimethylamino-PEG3 structure
Common Name Dimethylamino-PEG3
CAS Number 2741-30-2 Molecular Weight 177.24100
Density N/A Boiling Point N/A
Molecular Formula C8H19NO3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Dimethylamino-PEG3


Dimethylamino-PEG3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name 2-[2-[2-(dimethylamino)ethoxy]ethoxy]ethanol
Synonym More Synonyms

 Dimethylamino-PEG3 Biological Activity

Description Dimethylamino-PEG3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C8H19NO3
Molecular Weight 177.24100
Exact Mass 177.13600
PSA 41.93000

 Safety Information

HS Code 2922509090

 Synthetic Route

~46%

Dimethylamino-PEG3 Structure

Dimethylamino-PEG3

CAS#:2741-30-2

Literature: Rattay; Rettig Pharmazie, 1997 , vol. 52, # 9 p. 676 - 679

~%

Dimethylamino-PEG3 Structure

Dimethylamino-PEG3

CAS#:2741-30-2

Literature: van der Stelt,C. et al. Arzneimittel Forschung, 1964 , vol. 14, p. 1053 - 1055

 Customs

HS Code 2922509090
Summary 2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

 Synonyms

Kaolizer 23NP
23P
Dimethylaminoethoxyethoxy-ethanol
Ethanol,2-[2-[2-(dimethylamino)ethoxy]ethoxy]
Kaolizer 23
Dimethylaminotriaethylenalkohol
Kaolizer 23P
2-[2-(2-dimethylamino-ethoxy)-ethoxy]-ethanol
1-O<2'-Dimethylaminoethoxyethyl>ethylenglykol
2-{2-[2-(dimethylamino)ethoxy]ethoxy}ethan-1-ol
2-[2-(2-Dimethylamino-aethoxy)-aethoxy]-aethanol
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