Communic acid

Modify Date: 2024-02-02 10:22:28

Communic acid Structure
Communic acid structure
Common Name Communic acid
CAS Number 2761-77-5 Molecular Weight 302.451
Density 1.0±0.1 g/cm3 Boiling Point 414.0±34.0 °C at 760 mmHg
Molecular Formula C20H30O2 Melting Point N/A
MSDS N/A Flash Point 199.8±20.3 °C

 Use of Communic acid


Communic acid ((+)-Communic acid) is a natural compound isolated from the branches of Platycladus orientalis. Communic acid displays minimum inhibitory concentration of 31 μM and IC50 of 15 μM against M. tuberculosis H37Ra.Communic acid exhibits protective effects against UVB-induced skin aging[1][2][3].

 Names

Name Communic acid
Synonym More Synonyms

 Communic acid Biological Activity

Description Communic acid ((+)-Communic acid) is a natural compound isolated from the branches of Platycladus orientalis. Communic acid displays minimum inhibitory concentration of 31 μM and IC50 of 15 μM against M. tuberculosis H37Ra.Communic acid exhibits protective effects against UVB-induced skin aging[1][2][3].
Related Catalog
Target

15 μM (M. tuberculosis H37Ra) [2]

References

[1]. Samoylenko V, et al. Antiparasitic, nematicidal and antifouling constituents from Juniperus berries. Phytother Res. 2008;22(12):1570-1576.  

[2]. Carpenter CD, et al. Anti-mycobacterial natural products from the Canadian medicinal plant Juniperus communis. J Ethnopharmacol. 2012;143(2):695-700.  

[3]. Huh WB, et al. Brown Pine Leaf Extract and Its Active Component Trans-Communic Acid Inhibit UVB-Induced MMP-1 Expression by Targeting PI3K. PLoS One. 2015;10(6):e0128365. Published 2015 Jun 11.  

 Chemical & Physical Properties

Density 1.0±0.1 g/cm3
Boiling Point 414.0±34.0 °C at 760 mmHg
Molecular Formula C20H30O2
Molecular Weight 302.451
Flash Point 199.8±20.3 °C
Exact Mass 302.224579
PSA 37.30000
LogP 6.69
Vapour Pressure 0.0±2.1 mmHg at 25°C
Index of Refraction 1.520

 Safety Information

Hazard Codes Xi

 Synonyms

(1S,4aR,5S,8aR)-1,4a-Dimethyl-6-methylene-5-[(2E)-3-methyl-2,4-pentadien-1-yl]decahydro-1-naphthalenecarboxylic acid
1-Naphthalenecarboxylic acid, decahydro-1,4a-dimethyl-6-methylene-5-[(2E)-3-methyl-2,4-pentadien-1-yl]-, (1S,4aR,5S,8aR)-
Top Suppliers:I want be here




Get all suppliers and price by the below link:

Communic acid suppliers

Communic acid price