mGluR5 antagonist-1

Modify Date: 2024-01-10 18:13:17

mGluR5 antagonist-1 structure	Common Name	mGluR5 antagonist-1
	CAS Number	2761424-76-2	Molecular Weight	382.41
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₃H₁₈N₄O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of mGluR5 antagonist-1

mGluR5 antagonist-1 (compound 10) is a high-affinity mGluR5 antagonist, with an IC50 value of 11.5 nM. mGluR5 antagonist-1 has anti-depressant effect[1].

Name	mGluR5 antagonist-1

Description	mGluR5 antagonist-1 (compound 10) is a high-affinity mGluR5 antagonist, with an IC50 value of 11.5 nM. mGluR5 antagonist-1 has anti-depressant effect[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> GPCR/G Protein >> mGluR
References	[1]. Yonglei Du, et al. Novel substituted 4-(Arylethynyl)-Pyrrolo[2,3-d]pyrimidines negative allosteric modulators (NAMs) of the metabotropic glutamate receptor subtype 5 (mGlu5) Treat depressive disorder in mice. Eur J Med Chem. 2023.

Molecular Formula	C₂₃H₁₈N₄O₂
Molecular Weight	382.41