PHD2-IN-1

Modify Date: 2024-01-08 12:57:14

PHD2-IN-1 Structure
PHD2-IN-1 structure
Common Name PHD2-IN-1
CAS Number 2768219-28-7 Molecular Weight 446.88
Density N/A Boiling Point N/A
Molecular Formula C21H23ClN4O5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of PHD2-IN-1


PHD2-IN-1 is a potent and orally active inhibitor of HIF prolyl hydroxylase 2 (PHD2) with an IC50 of 22.53 nM. PHD2-IN-1 can be used for anemia research[1].

 Names

Name PHD2-IN-1

 PHD2-IN-1 Biological Activity

Description PHD2-IN-1 is a potent and orally active inhibitor of HIF prolyl hydroxylase 2 (PHD2) with an IC50 of 22.53 nM. PHD2-IN-1 can be used for anemia research[1].
Related Catalog
References

[1]. Wu Y, et.al. Preferred Conformation-Guided Discovery of Potent and Orally Active HIF Prolyl Hydroxylase 2 Inhibitors for the Treatment of Anemia. J Med Chem. 2023 Jul 13;66(13):8545-8563.  

 Chemical & Physical Properties

Molecular Formula C21H23ClN4O5
Molecular Weight 446.88