MRV03-037

Modify Date: 2024-04-03 11:31:59

MRV03-037 Structure
MRV03-037 structure
Common Name MRV03-037
CAS Number 2797066-28-3 Molecular Weight 230.07
Density N/A Boiling Point N/A
Molecular Formula C9H19BN2O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of MRV03-037


MRV03-037 is a selective colibactin-activated peptidase (ClbP) inhibitor that blocks the genotoxic effect of Colibactin (HY-145930) on eukaryotic cells. MRV03-037 prevents gut bacterial genotoxin production[1].

 Names

Name MRV03-037

 MRV03-037 Biological Activity

Description MRV03-037 is a selective colibactin-activated peptidase (ClbP) inhibitor that blocks the genotoxic effect of Colibactin (HY-145930) on eukaryotic cells. MRV03-037 prevents gut bacterial genotoxin production[1].
Related Catalog
In Vitro MRV03-037 (compound 1; 0.01 nM-0.1 mM for 1 h) inhibits ClbP acitivity in E. coli BL21 overexpressing ClbP[1].
References

[1]. Volpe MR, et al. A small molecule inhibitor prevents gut bacterial genotoxin production. Nat Chem Biol. 2022 Oct 17.

 Chemical & Physical Properties

Molecular Formula C9H19BN2O4
Molecular Weight 230.07
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