Cbl-b-IN-8

Modify Date: 2024-01-08 20:12:32

Use of Cbl-b-IN-8

Cbl-b-IN-8 (Compound 293) is a casitas B-lineage lymphoma-b (Cbl-b) and c-Cbl inhibitor with IC50s of 5.5 nM and 7.8 nM, respectively[1].

Name	Cbl-b-IN-8

Description	Cbl-b-IN-8 (Compound 293) is a casitas B-lineage lymphoma-b (Cbl-b) and c-Cbl inhibitor with IC50s of 5.5 nM and 7.8 nM, respectively[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Metabolic Enzyme/Protease >> E1/E2/E3 Enzyme
Target	IC50: 5.5 nM (Cbl-b), 7.8 nM (c-Cbl)[1]
References	[1]. Jun Liang, et al. Lactams as cbl-b inhibitors. Patent WO2022169997A1.

Molecular Formula	C₃₅H₄₄F₃N₇O₃
Molecular Weight	667.76