Pomalidomide-5-C8-NH2 hydrochloride

Modify Date: 2024-03-30 14:01:18

Pomalidomide-5-C8-NH2 hydrochloride Structure
Pomalidomide-5-C8-NH2 hydrochloride structure
Common Name Pomalidomide-5-C8-NH2 hydrochloride
CAS Number 2863635-03-2 Molecular Weight 436.93
Density N/A Boiling Point N/A
Molecular Formula C21H29ClN4O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Pomalidomide-5-C8-NH2 hydrochloride


Pomalidomide-5-C8-NH2 hydrochloride is the Pomalidomide (HY-10984)-based cereblon (CRBN) ligand used in the recruitment of CRBN protein. Pomalidomide-5-C8-NH2 hydrochloride can be connected to the ligand for protein by a linker to form PROTAC[1].

 Names

Name Pomalidomide-5-C8-NH2 hydrochloride

 Pomalidomide-5-C8-NH2 hydrochloride Biological Activity

Description Pomalidomide-5-C8-NH2 hydrochloride is the Pomalidomide (HY-10984)-based cereblon (CRBN) ligand used in the recruitment of CRBN protein. Pomalidomide-5-C8-NH2 hydrochloride can be connected to the ligand for protein by a linker to form PROTAC[1].
Related Catalog
References

[1]. Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985.  

 Chemical & Physical Properties

Molecular Formula C21H29ClN4O4
Molecular Weight 436.93