Dehydrotrametenolic acid

Modify Date: 2024-01-02 15:22:18

Dehydrotrametenolic acid structure	Common Name	Dehydrotrametenolic acid
	CAS Number	29220-16-4	Molecular Weight	454.684
	Density	1.08±0.1 g/cm3	Boiling Point	585.4±50.0 °C at 760 mmHg
	Molecular Formula	C₃₀H₄₆O₃	Melting Point	257-259 ºC
	MSDS	N/A	Flash Point	321.9±26.6 °C

Use of Dehydrotrametenolic acid

3-Dehydrotrametenolic acid, isolated from the sclerotium of Poria cocos, is a lactate dehydrogenase (LDH) inhibitor. 3-Dehydrotrametenolic acid promotes adipocyte differentiation in vitro and acts as an insulin sensitizer in vivo. 3-Dehydrotrametenolic acid induces apoptosis and has anticancer activity[1][2].

Name	dehydrotrametenolic acid
Synonym	More Synonyms

Description	3-Dehydrotrametenolic acid, isolated from the sclerotium of Poria cocos, is a lactate dehydrogenase (LDH) inhibitor. 3-Dehydrotrametenolic acid promotes adipocyte differentiation in vitro and acts as an insulin sensitizer in vivo. 3-Dehydrotrametenolic acid induces apoptosis and has anticancer activity[1][2].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer Signaling Pathways >> Metabolic Enzyme/Protease >> Lactate Dehydrogenase
Target	Lactate dehydrogenase [1]
References	[1]. De Nicola GR, et al. Novel gram-scale production of enantiopure R-sulforaphane from Tuscan black kale seeds. Molecules. 2014 May 27;19(6):6975-86. [2]. Abdull Razis AF, et al. The natural chemopreventive phytochemical R-sulforaphane is a far more potent inducer of the carcinogen-detoxifying enzyme systems in rat liver and lung than the S-isomer. Int J Cancer. 2011 Jun 15;128(12):2775-82.

Density	1.08±0.1 g/cm3
Boiling Point	585.4±50.0 °C at 760 mmHg
Melting Point	257-259 ºC
Molecular Formula	C₃₀H₄₆O₃
Molecular Weight	454.684
Flash Point	321.9±26.6 °C
Exact Mass	454.344696
PSA	57.53000
LogP	8.50
Vapour Pressure	0.0±3.7 mmHg at 25°C
Index of Refraction	1.557
Storage condition	2-8℃
Water Solubility	Insuluble (1.0E-5 g/L) (25 ºC)