PROTAC EGFR degrader 8

Modify Date: 2024-04-07 08:58:27

PROTAC EGFR degrader 8 structure	Common Name	PROTAC EGFR degrader 8
	CAS Number	2925923-46-0	Molecular Weight	796.32
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₄₀H₄₆ClN₁₁O₅	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of PROTAC EGFR degrader 8

PROTAC EGFR degrader 8 (T-184) is a PROTAC EGFR degrader. PROTAC EGFR degrader 8 degrades EGFR in HCC827 cell with a DC50 of 15.56 nM. PROTAC EGFR degrader 8 inhibits H1975, PC-9, HCC827 cell growth with IC50s of 7.72 nM, 121.9 nM, 14.21 nM. PROTAC EGFR degrader 8 can be used for research of cancer, especially NSCLC[1].

Name	PROTAC EGFR degrader 8

Description	PROTAC EGFR degrader 8 (T-184) is a PROTAC EGFR degrader. PROTAC EGFR degrader 8 degrades EGFR in HCC827 cell with a DC50 of 15.56 nM. PROTAC EGFR degrader 8 inhibits H1975, PC-9, HCC827 cell growth with IC50s of 7.72 nM, 121.9 nM, 14.21 nM. PROTAC EGFR degrader 8 can be used for research of cancer, especially NSCLC[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> JAK/STAT Signaling >> EGFR Signaling Pathways >> Protein Tyrosine Kinase/RTK >> EGFR Signaling Pathways >> PROTAC >> PROTAC
References	[1]. Liang, Apeng, et al. Compounds for EGFR protein degradation and uses thereof.Patent. CN116135852.

Molecular Formula	C₄₀H₄₆ClN₁₁O₅
Molecular Weight	796.32

PROTAC EGFR degrader 8

Use of PROTAC EGFR degrader 8

Names

PROTAC EGFR degrader 8 Biological Activity

Chemical & Physical Properties