UNC8153 TFA
Modify Date: 2024-01-08 14:03:47
UNC8153 TFA structure
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Common Name | UNC8153 TFA | ||
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| CAS Number | 2929304-61-8 | Molecular Weight | 697.70 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C35H38F3N5O7 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of UNC8153 TFAUNC8153 TFA is a potent and selective nuclear receptor-binding SET domain-containing 2 (NSD2)-targeted degrader with a Kd of 24 nM. UNC8153 TFA reduces the cellular levels of both NSD2 protein and the H3K36me2 chromatin mark. UNC8153 TFA contains a simple warhead that confers proteasome-dependent degradation of NSD2[1]. |
| Name | UNC8153 TFA |
|---|
| Description | UNC8153 TFA is a potent and selective nuclear receptor-binding SET domain-containing 2 (NSD2)-targeted degrader with a Kd of 24 nM. UNC8153 TFA reduces the cellular levels of both NSD2 protein and the H3K36me2 chromatin mark. UNC8153 TFA contains a simple warhead that confers proteasome-dependent degradation of NSD2[1]. |
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| Molecular Formula | C35H38F3N5O7 |
|---|---|
| Molecular Weight | 697.70 |