h-NTPDase-IN-4

Modify Date: 2024-01-12 13:32:21

h-NTPDase-IN-4 Structure
h-NTPDase-IN-4 structure
Common Name h-NTPDase-IN-4
CAS Number 2939933-09-0 Molecular Weight 560.36
Density N/A Boiling Point N/A
Molecular Formula C22H8F12N2S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of h-NTPDase-IN-4


h-NTPDase-IN-4 (compound 4c) is a pan-inhibitor of NTPDase with IC50s of 3.58 μM (h-NTPDase1), 10.21 μM (h-NTPDase2), 0.13 μM (h-NTPDase3), 13.57 μM (h- NTPDase8).

 Names

Name h-NTPDase-IN-4

 h-NTPDase-IN-4 Biological Activity

Description h-NTPDase-IN-4 (compound 4c) is a pan-inhibitor of NTPDase with IC50s of 3.58 μM (h-NTPDase1), 10.21 μM (h-NTPDase2), 0.13 μM (h-NTPDase3), 13.57 μM (h- NTPDase8).
Related Catalog
Target

IC50: 3.58 μM (h-NTPDase1), 10.21 μM (h-NTPDase2), 0.13 μM (h-NTPDase3), 13.57 μM (h- NTPDase8)

References

[1]. Zaman G, Ullah S, Uzair M, et al. Synthesis of Thieno [3, 2‐d] pyrimidine Derivatives through Sequential SNAr and Suzuki Reactions as Selective h‐NTPDases Inhibitors[J]. ChemMedChem, 2023: e202300165.

 Chemical & Physical Properties

Molecular Formula C22H8F12N2S
Molecular Weight 560.36