Tabersonine hydrochloride

Modify Date: 2024-01-11 11:11:00

Tabersonine hydrochloride Structure
Tabersonine hydrochloride structure
Common Name Tabersonine hydrochloride
CAS Number 29479-00-3 Molecular Weight 372.88800
Density N/A Boiling Point N/A
Molecular Formula C21H25ClN2O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Tabersonine hydrochloride


Tabersonine is an indole alkaloid mainly isolated from Catharanthus roseus. Tabersonine disrupts Aβ(1-42) aggregation and ameliorates Aβ aggregate-induced cytotoxicity. Tabersonine has anti-inflammatory activities and is a potential therapeutic candidate for the treatment of ALI/ARDS[1].

 Names

Name (-)-tabersonine hydrochloride
Synonym More Synonyms

 Tabersonine hydrochloride Biological Activity

Description Tabersonine is an indole alkaloid mainly isolated from Catharanthus roseus. Tabersonine disrupts Aβ(1-42) aggregation and ameliorates Aβ aggregate-induced cytotoxicity. Tabersonine has anti-inflammatory activities and is a potential therapeutic candidate for the treatment of ALI/ARDS[1].
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References

[1]. Zhang D, et al. Tabersonine attenuates lipopolysaccharide-induced acute lung injury via suppressing TRAF6 ubiquitination. Biochem Pharmacol. 2018 Aug;154:183-192.

 Chemical & Physical Properties

Molecular Formula C21H25ClN2O2
Molecular Weight 372.88800
Exact Mass 372.16000
PSA 41.57000
LogP 4.09910
Storage condition -20℃

 Synonyms

ent-2,3,6,7-Tetradehydro-aspidospermidin-3-carbonsaeure-methylester, Hydrochlorid
ent-2,3,6,7-tetradehydro-aspidospermidine-3-carboxylic acid methyl ester, hydrochloride
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