NLRP3-IN-21

Modify Date: 2024-01-14 03:44:28

NLRP3-IN-21 structure	Common Name	NLRP3-IN-21
	CAS Number	2956791-61-8	Molecular Weight	529.32
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₀H₁₃Cl₂F₃N₆O₂S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of NLRP3-IN-21

NLRP3-IN-21 (compound L38) is a NLRP3 inflammasome inhibitor with inflammatory properties. NLRP3-IN-21 inhibits NLRP3 inflammasome activation and pyroptosis by suppressing gasdermin D cleavage, ASC oligomerization, and NLRP3 inflammasome assembly[1].

Name	NLRP3-IN-21

Description	NLRP3-IN-21 (compound L38) is a NLRP3 inflammasome inhibitor with inflammatory properties. NLRP3-IN-21 inhibits NLRP3 inflammasome activation and pyroptosis by suppressing gasdermin D cleavage, ASC oligomerization, and NLRP3 inflammasome assembly[1].
Related Catalog	Signaling Pathways >> Immunology/Inflammation >> NOD-like Receptor (NLR) Research Areas >> Inflammation/Immunology
References	[1]. Na Li, et al. Discovery of Triazinone Derivatives as Novel, Specific, and Direct NLRP3 Inflammasome Inhibitors for the Treatment of DSS-Induced Ulcerative Colitis. J Med Chem. 2023 Oct 12;66(19):13428-13451.

Molecular Formula	C₂₀H₁₃Cl₂F₃N₆O₂S
Molecular Weight	529.32

NLRP3-IN-21

Use of NLRP3-IN-21

Names

NLRP3-IN-21 Biological Activity

Chemical & Physical Properties