2-(3-Phenoxyphenyl)propanoic acid

Modify Date: 2024-01-03 17:22:21

2-(3-Phenoxyphenyl)propanoic acid Structure
2-(3-Phenoxyphenyl)propanoic acid structure
Common Name 2-(3-Phenoxyphenyl)propanoic acid
CAS Number 29679-58-1 Molecular Weight 242.270
Density 1.2±0.1 g/cm3 Boiling Point 381.3±25.0 °C at 760 mmHg
Molecular Formula C15H14O3 Melting Point N/A
MSDS N/A Flash Point 141.7±16.7 °C

 Use of 2-(3-Phenoxyphenyl)propanoic acid


Fenoprofen (LILLY-53858) is a nonsteroidal anti-inflammatory agent (NSAID). Fenoprofen can be used to to relieve symptoms of arthritis (osteoarthritis and rheumatoid arthritis), such as inflammation, swelling, stiffness, and joint pain. Fenoprofen is an allosteric enhancer for melanocortin receptors. Fenoprofen also increases ERK1/2 activation[1][2].

 Names

Name α-methyl-3-phenoxybenzeneacetic acid
Synonym More Synonyms

 2-(3-Phenoxyphenyl)propanoic acid Biological Activity

Description Fenoprofen (LILLY-53858) is a nonsteroidal anti-inflammatory agent (NSAID). Fenoprofen can be used to to relieve symptoms of arthritis (osteoarthritis and rheumatoid arthritis), such as inflammation, swelling, stiffness, and joint pain. Fenoprofen is an allosteric enhancer for melanocortin receptors. Fenoprofen also increases ERK1/2 activation[1][2].
Related Catalog
References

[1]. Tahereh Rezaei, et al. A universal methodology for reliable predicting the non-steroidal anti-inflammatory drug solubility in supercritical carbon dioxide. Sci Rep. 2022 Jan 20;12(1):1043.

[2]. Xiao-Chen Yuan, et al. Fenoprofen-An Old Drug Rediscovered as a Biased Allosteric Enhancer for Melanocortin Receptors. ACS Chem Neurosci. 2019 Mar 20;10(3):1066-1074.

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 381.3±25.0 °C at 760 mmHg
Molecular Formula C15H14O3
Molecular Weight 242.270
Flash Point 141.7±16.7 °C
Exact Mass 242.094299
PSA 46.53000
LogP 3.84
Vapour Pressure 0.0±0.9 mmHg at 25°C
Index of Refraction 1.583

 Safety Information

Hazard Codes Xi

 Precursor & DownStream

Precursor  0

DownStream  1

 Synonyms

Fenoprofen
2-[3-(phenyloxy)phenyl]propanoic acid
PROGESIC
Benzeneacetic acid, α-methyl-3-phenoxy-, (±)-
3-(4-phenoxyphenyl)propionic acid
p1316-b<br> 3-(4-phenoxyphenyl)propionic acid
UNII:RA33EAC7KY
Fenopron
Feprona
2-(3-Phenoxyphenyl)propanoic acid
Benzeneacetic acid, α-methyl-3-phenoxy-