PD-1/PD-L1-IN-33

Modify Date: 2024-01-17 12:11:21

PD-1/PD-L1-IN-33 Structure
PD-1/PD-L1-IN-33 structure
Common Name PD-1/PD-L1-IN-33
CAS Number 2975602-78-7 Molecular Weight 425.53
Density N/A Boiling Point N/A
Molecular Formula C26H27N5O Melting Point N/A
MSDS N/A Flash Point N/A

 Use of PD-1/PD-L1-IN-33


PD-1/PD-L1-IN-33 (Compound N11) is a PD-1/PD-L1 inhibitor. PD-1/PD-L1-IN-33 inhibits PD-1 and PD-L1 interaction with an IC50: 6.3 nM. PD-1/PD-L1-IN-33 promotes T-cell proliferation, activation, and infiltration into tumor spheres. PD-1/PD-L1-IN-33 has immunomodulatory and anticancer activity[1].

 Names

Name PD-1/PD-L1-IN-33

 PD-1/PD-L1-IN-33 Biological Activity

Description PD-1/PD-L1-IN-33 (Compound N11) is a PD-1/PD-L1 inhibitor. PD-1/PD-L1-IN-33 inhibits PD-1 and PD-L1 interaction with an IC50: 6.3 nM. PD-1/PD-L1-IN-33 promotes T-cell proliferation, activation, and infiltration into tumor spheres. PD-1/PD-L1-IN-33 has immunomodulatory and anticancer activity[1].
Related Catalog
References

[1]. Yangyang Meng, et al. Novel 4-Arylindolines Containing a Pyrido[3,2-d]pyrimidine Moiety as the Programmed Cell Death-1/Programmed Cell Death-Ligand 1 Interaction Inhibitors for Tumor Immunotherapy. J. Med. Chem. 2023.

 Chemical & Physical Properties

Molecular Formula C26H27N5O
Molecular Weight 425.53