l-Sotalol
Modify Date: 2024-04-10 20:25:54
l-Sotalol structure
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Common Name | l-Sotalol | ||
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| CAS Number | 30236-31-8 | Molecular Weight | 272.364 | |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 443.3±55.0 °C at 760 mmHg | |
| Molecular Formula | C12H20N2O3S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 221.9±31.5 °C | |
Use of l-Sotalol(-)-Sotalol is a non-selective competitive beta-adrenergic receptor blocker that also shows Class III antiarrhythmic properties. |
| Name | N-{4-[(1R)-1-Hydroxy-2-(isopropylamino)ethyl]phenyl}methanesulfonamide |
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| Synonym | More Synonyms |
| Description | (-)-Sotalol is a non-selective competitive beta-adrenergic receptor blocker that also shows Class III antiarrhythmic properties. |
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| References | 1. Darpo B, Karnad DR, Badilini F, Florian J, Garnett CE, Kothari S, Panicker GK, Sarapa N. Are women more susceptible than men to drug-induced QT prolongation? Concentration-QTc modelling in a phase 1 study with oral rac-sotalol. Br J Clin Pharmacol. 2014 Mar;77(3):522-31. doi: 10.1111/bcp.12201. PubMed PMID: 23819796; PubMed Central PMCID: PMC4371537. |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 443.3±55.0 °C at 760 mmHg |
| Molecular Formula | C12H20N2O3S |
| Molecular Weight | 272.364 |
| Flash Point | 221.9±31.5 °C |
| Exact Mass | 272.119476 |
| LogP | 0.32 |
| Vapour Pressure | 0.0±1.1 mmHg at 25°C |
| Index of Refraction | 1.571 |
| N-{4-[(1R)-1-Hydroxy-2-(isopropylamino)ethyl]phenyl}methanesulfonamide |
| Methanesulfonamide, N-[4-[(1R)-1-hydroxy-2-[(1-methylethyl)amino]ethyl]phenyl]- |
| N-{4-[(1R)-1-hydroxy-2-(propan-2-ylamino)ethyl]phenyl}methanesulfonamide |