JB002

Modify Date: 2024-07-16 18:42:36

JB002 Structure
JB002 structure
Common Name JB002
CAS Number 30408-07-2 Molecular Weight 293.32
Density N/A Boiling Point N/A
Molecular Formula C18H15NO3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of JB002


JB002 is a myosin II inhibitor, with an IC50 of ≤10 μM. JB002 can be used for the research of muscle spasticity, chronic musculoskeletal pain, and hypertrophic cardiomyopathy[1].

 Names

Name JB002

 JB002 Biological Activity

Description JB002 is a myosin II inhibitor, with an IC50 of ≤10 μM. JB002 can be used for the research of muscle spasticity, chronic musculoskeletal pain, and hypertrophic cardiomyopathy[1].
Related Catalog
Target

IC50: ≤10 μM (myosin II)[1]

In Vitro JB002 在心脏和骨骼肌球蛋白之间表现出良好的选择性,但对非肌肉 IIB 没有可检测的活性[1]。
References

[1]. Smith JD, et, al. Isoform selectivities of novel 4-hydroxycoumarin imines as inhibitors of myosin II. Eur J Med Chem. 2022 Dec 12;247:115008.  

 Chemical & Physical Properties

Molecular Formula C18H15NO3
Molecular Weight 293.32