4-chloro-6-fluoro-1,7-

Modify Date: 2024-01-16 20:33:57

4-chloro-6-fluoro-1,7- Structure
4-chloro-6-fluoro-1,7- structure
 Common Name 4-chloro-6-fluoro-1,7-
CAS Number 305371-18-0 Molecular Weight 207.59200
Density N/A Boiling Point N/A
Molecular Formula C9H3ClFN3 Melting Point N/A
MSDS N/A Flash Point N/A

 Names

Name 4-chloro-6-fluoro-1,7-naphthyridine-3-carbonitrile

 Chemical & Physical Properties

Molecular Formula C9H3ClFN3
Molecular Weight 207.59200
Exact Mass 207.00000
PSA 49.57000
LogP 2.29398

 Synthetic Route

6-fluoro-4-hydroxy-1,7-naphthyridine-3-carbonitrile structure

6-fluoro-4-hydr...

CAS#:305371-17-9

~92%

4-chloro-6-fluoro-1,7- Structure

4-chloro-6-fluo...

CAS#:305371-18-0

Literature: Wyeth Holdings Corporation Patent: EP1171440 B1, 2004 ; Location in patent: Page 54 ;
2-Fluoro-5-nitropyridine structure

2-Fluoro-5-nitr...

CAS#:456-24-6

~%

4-chloro-6-fluoro-1,7- Structure

4-chloro-6-fluo...

CAS#:305371-18-0

Literature: Wissner, Allan; Hamann, Philip R.; Nilakantan, Ramaswamy; Greenberger, Lee M.; Ye, Fei; Rapuano, Timothy A.; Loganzo, Frank Bioorganic and Medicinal Chemistry Letters, 2004 , vol. 14, # 6 p. 1411 - 1416
2-Chloro-5-nitropyridine structure

2-Chloro-5-nitr...

CAS#:4548-45-2

~%

4-chloro-6-fluoro-1,7- Structure

4-chloro-6-fluo...

CAS#:305371-18-0

Literature: Wissner, Allan; Hamann, Philip R.; Nilakantan, Ramaswamy; Greenberger, Lee M.; Ye, Fei; Rapuano, Timothy A.; Loganzo, Frank Bioorganic and Medicinal Chemistry Letters, 2004 , vol. 14, # 6 p. 1411 - 1416
5-Amino-2-fluoropyridine structure

5-Amino-2-fluor...

CAS#:1827-27-6

~%

4-chloro-6-fluoro-1,7- Structure

4-chloro-6-fluo...

CAS#:305371-18-0

Literature: Wissner, Allan; Hamann, Philip R.; Nilakantan, Ramaswamy; Greenberger, Lee M.; Ye, Fei; Rapuano, Timothy A.; Loganzo, Frank Bioorganic and Medicinal Chemistry Letters, 2004 , vol. 14, # 6 p. 1411 - 1416
Boc-5-Amino-2-fluoropyridine structure

Boc-5-Amino-2-f...

CAS#:171178-41-9

~%

4-chloro-6-fluoro-1,7- Structure

4-chloro-6-fluo...

CAS#:305371-18-0

Literature: Wissner, Allan; Hamann, Philip R.; Nilakantan, Ramaswamy; Greenberger, Lee M.; Ye, Fei; Rapuano, Timothy A.; Loganzo, Frank Bioorganic and Medicinal Chemistry Letters, 2004 , vol. 14, # 6 p. 1411 - 1416
5-((TERT-BUTOXYCARBONYL)AMINO)-2-FLUOROISONICOTINIC ACID structure

5-((TERT-BUTOXY...

CAS#:171178-42-0

~%

4-chloro-6-fluoro-1,7- Structure

4-chloro-6-fluo...

CAS#:305371-18-0

Literature: Wissner, Allan; Hamann, Philip R.; Nilakantan, Ramaswamy; Greenberger, Lee M.; Ye, Fei; Rapuano, Timothy A.; Loganzo, Frank Bioorganic and Medicinal Chemistry Letters, 2004 , vol. 14, # 6 p. 1411 - 1416
methyl 2-fluoro-5-[(2-methylpropan-2-yl)oxycarbonylamino]pyridine-4-carboxylate structure

methyl 2-fluoro...

CAS#:305371-15-7

~%

4-chloro-6-fluoro-1,7- Structure

4-chloro-6-fluo...

CAS#:305371-18-0

Literature: Wissner, Allan; Hamann, Philip R.; Nilakantan, Ramaswamy; Greenberger, Lee M.; Ye, Fei; Rapuano, Timothy A.; Loganzo, Frank Bioorganic and Medicinal Chemistry Letters, 2004 , vol. 14, # 6 p. 1411 - 1416
[6-FLUORO-4-(3-NITRILOPROPIONYL)PYRIDIN-3-YL]CARBAMIC ACID TERT-BUTYL ESTER structure

[6-FLUORO-4-(3-...

CAS#:305371-16-8

~%

4-chloro-6-fluoro-1,7- Structure

4-chloro-6-fluo...

CAS#:305371-18-0

Literature: Wissner, Allan; Hamann, Philip R.; Nilakantan, Ramaswamy; Greenberger, Lee M.; Ye, Fei; Rapuano, Timothy A.; Loganzo, Frank Bioorganic and Medicinal Chemistry Letters, 2004 , vol. 14, # 6 p. 1411 - 1416
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