4-(3-chloro-4-fluorophenylamino)-6-fluoro-1,7-naphthyridine-3-carbonitrile

Modify Date: 2024-01-06 22:28:24

4-(3-chloro-4-fluorophenylamino)-6-fluoro-1,7-naphthyridine-3-carbonitrile Structure
4-(3-chloro-4-fluorophenylamino)-6-fluoro-1,7-naphthyridine-3-carbonitrile structure
 Common Name 4-(3-chloro-4-fluorophenylamino)-6-fluoro-1,7-naphthyridine-3-carbonitrile
CAS Number 305371-33-9 Molecular Weight 316.69300
Density N/A Boiling Point N/A
Molecular Formula C15H7ClF2N4 Melting Point N/A
MSDS N/A Flash Point N/A

 Names

Name 4-(3-chloro-4-fluoroanilino)-6-fluoro-1,7-naphthyridine-3-carbonitrile

 Chemical & Physical Properties

Molecular Formula C15H7ClF2N4
Molecular Weight 316.69300
Exact Mass 316.03300
PSA 64.83000
LogP 3.59858

 Safety Information

HS Code 2933990090

 Synthetic Route

3-Chloro-4-fluoroaniline structure

3-Chloro-4-fluo...

CAS#:367-21-5

4-chloro-6-fluoro-1,7- structure

4-chloro-6-fluo...

CAS#:305371-18-0

~85%

4-(3-chloro-4-fluorophenylamino)-6-fluoro-1,7-naphthyridine-3-carbonitrile Structure

4-(3-chloro-4-f...

CAS#:305371-33-9

Literature: Wyeth Holdings Corporation Patent: EP1171440 B1, 2004 ; Location in patent: Page 57 ;
2-Fluoro-5-nitropyridine structure

2-Fluoro-5-nitr...

CAS#:456-24-6

~%

4-(3-chloro-4-fluorophenylamino)-6-fluoro-1,7-naphthyridine-3-carbonitrile Structure

4-(3-chloro-4-f...

CAS#:305371-33-9

Literature: Wissner, Allan; Hamann, Philip R.; Nilakantan, Ramaswamy; Greenberger, Lee M.; Ye, Fei; Rapuano, Timothy A.; Loganzo, Frank Bioorganic and Medicinal Chemistry Letters, 2004 , vol. 14, # 6 p. 1411 - 1416
2-Chloro-5-nitropyridine structure

2-Chloro-5-nitr...

CAS#:4548-45-2

~%

4-(3-chloro-4-fluorophenylamino)-6-fluoro-1,7-naphthyridine-3-carbonitrile Structure

4-(3-chloro-4-f...

CAS#:305371-33-9

Literature: Wissner, Allan; Hamann, Philip R.; Nilakantan, Ramaswamy; Greenberger, Lee M.; Ye, Fei; Rapuano, Timothy A.; Loganzo, Frank Bioorganic and Medicinal Chemistry Letters, 2004 , vol. 14, # 6 p. 1411 - 1416
5-Amino-2-fluoropyridine structure

5-Amino-2-fluor...

CAS#:1827-27-6

~%

4-(3-chloro-4-fluorophenylamino)-6-fluoro-1,7-naphthyridine-3-carbonitrile Structure

4-(3-chloro-4-f...

CAS#:305371-33-9

Literature: Wissner, Allan; Hamann, Philip R.; Nilakantan, Ramaswamy; Greenberger, Lee M.; Ye, Fei; Rapuano, Timothy A.; Loganzo, Frank Bioorganic and Medicinal Chemistry Letters, 2004 , vol. 14, # 6 p. 1411 - 1416
Boc-5-Amino-2-fluoropyridine structure

Boc-5-Amino-2-f...

CAS#:171178-41-9

~%

4-(3-chloro-4-fluorophenylamino)-6-fluoro-1,7-naphthyridine-3-carbonitrile Structure

4-(3-chloro-4-f...

CAS#:305371-33-9

Literature: Wissner, Allan; Hamann, Philip R.; Nilakantan, Ramaswamy; Greenberger, Lee M.; Ye, Fei; Rapuano, Timothy A.; Loganzo, Frank Bioorganic and Medicinal Chemistry Letters, 2004 , vol. 14, # 6 p. 1411 - 1416
5-((TERT-BUTOXYCARBONYL)AMINO)-2-FLUOROISONICOTINIC ACID structure

5-((TERT-BUTOXY...

CAS#:171178-42-0

~%

4-(3-chloro-4-fluorophenylamino)-6-fluoro-1,7-naphthyridine-3-carbonitrile Structure

4-(3-chloro-4-f...

CAS#:305371-33-9

Literature: Wissner, Allan; Hamann, Philip R.; Nilakantan, Ramaswamy; Greenberger, Lee M.; Ye, Fei; Rapuano, Timothy A.; Loganzo, Frank Bioorganic and Medicinal Chemistry Letters, 2004 , vol. 14, # 6 p. 1411 - 1416
6-fluoro-4-hydroxy-1,7-naphthyridine-3-carbonitrile structure

6-fluoro-4-hydr...

CAS#:305371-17-9

~%

4-(3-chloro-4-fluorophenylamino)-6-fluoro-1,7-naphthyridine-3-carbonitrile Structure

4-(3-chloro-4-f...

CAS#:305371-33-9

Literature: Wissner, Allan; Hamann, Philip R.; Nilakantan, Ramaswamy; Greenberger, Lee M.; Ye, Fei; Rapuano, Timothy A.; Loganzo, Frank Bioorganic and Medicinal Chemistry Letters, 2004 , vol. 14, # 6 p. 1411 - 1416
methyl 2-fluoro-5-[(2-methylpropan-2-yl)oxycarbonylamino]pyridine-4-carboxylate structure

methyl 2-fluoro...

CAS#:305371-15-7

~%

4-(3-chloro-4-fluorophenylamino)-6-fluoro-1,7-naphthyridine-3-carbonitrile Structure

4-(3-chloro-4-f...

CAS#:305371-33-9

Literature: Wissner, Allan; Hamann, Philip R.; Nilakantan, Ramaswamy; Greenberger, Lee M.; Ye, Fei; Rapuano, Timothy A.; Loganzo, Frank Bioorganic and Medicinal Chemistry Letters, 2004 , vol. 14, # 6 p. 1411 - 1416
[6-FLUORO-4-(3-NITRILOPROPIONYL)PYRIDIN-3-YL]CARBAMIC ACID TERT-BUTYL ESTER structure

[6-FLUORO-4-(3-...

CAS#:305371-16-8

~%

4-(3-chloro-4-fluorophenylamino)-6-fluoro-1,7-naphthyridine-3-carbonitrile Structure

4-(3-chloro-4-f...

CAS#:305371-33-9

Literature: Wissner, Allan; Hamann, Philip R.; Nilakantan, Ramaswamy; Greenberger, Lee M.; Ye, Fei; Rapuano, Timothy A.; Loganzo, Frank Bioorganic and Medicinal Chemistry Letters, 2004 , vol. 14, # 6 p. 1411 - 1416

 Customs

HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
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Chemsrc provides CAS#:305371-33-9 MSDS, density, melting point, boiling point, structure, etc. Its name is 4-(3-chloro-4-fluorophenylamino)-6-fluoro-1,7-naphthyridine-3-carbonitrile>> amp version: 4-(3-chloro-4-fluorophenylamino)-6-fluoro-1,7-naphthyridine-3-carbonitrile

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