3-Amino-4-phenylbutyric acid hydrochloride

Modify Date: 2024-01-09 18:12:54

3-Amino-4-phenylbutyric acid hydrochloride structure	Common Name	3-Amino-4-phenylbutyric acid hydrochloride
	CAS Number	3060-41-1	Molecular Weight	215.677
	Density	1.161g/cm3	Boiling Point	327.8ºC at 760 mmHg
	Molecular Formula	C₁₀H₁₄ClNO₂	Melting Point	194-201ºC
	MSDS	N/A	Flash Point	152.1ºC

Use of 3-Amino-4-phenylbutyric acid hydrochloride

Phenibut (β-Phenyl-GABA) hydrochloride is an orally active GABA-B agonist[1]. Phenibut hydrochloride acts as a GABA-mimetic, primarily at GABAB receptors. Phenibut hydrochloride has anxiolytic and nootropic (cognition enhancing) effects[2].

Name	3-Amino-4-phenylbutyric acid hydrochloride
Synonym	More Synonyms

Description	Phenibut (β-Phenyl-GABA) hydrochloride is an orally active GABA-B agonist[1]. Phenibut hydrochloride acts as a GABA-mimetic, primarily at GABAB receptors. Phenibut hydrochloride has anxiolytic and nootropic (cognition enhancing) effects[2].
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> GABA Receptor Research Areas >> Neurological Disease Signaling Pathways >> Neuronal Signaling >> GABA Receptor
Target	GABA-B[1][2]
In Vitro	Phenibut hydrochloride is a neuropsychotropic agent. Phenibut hydrochloride also stimulates dopamine receptors and antagonizes β-phenethylamine (PEA), a putative endogenous anxiogenic[2].
References	[1]. Ahuja T, et al. Phenibut (β-Phenyl-γ-aminobutyric Acid) Dependence and Management of Withdrawal: EmergingNootropics of Abuse. Case Rep Psychiatry. 2018 Apr 30;2018:9864285. [2]. Lapin I. Phenibut (beta-phenyl-GABA): a tranquilizer and nootropic drug. CNS Drug Rev. 2001 Winter;7(4):471-81.

Density	1.161g/cm3
Boiling Point	327.8ºC at 760 mmHg
Melting Point	194-201ºC
Molecular Formula	C₁₀H₁₄ClNO₂
Molecular Weight	215.677
Flash Point	152.1ºC
Exact Mass	215.071304
PSA	63.32000
LogP	2.53340

Hazard Codes	Xi
HS Code	2922499990

3,3-diethoxycar...

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3-Amino-4-pheny...

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Literature: Kreile, D. R.; Slavinskaya, V. A.; Ziemelis, K. M.; Tomsons, U. A.; Gutmanis, A. E.; et al. J. Appl. Chem. USSR (Engl. Transl.), 1982 , vol. 55, # 4 p. 972 - 974,902 - 904

4-Phenyl-2-pyrr...

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~55%

3-Amino-4-pheny...

CAS#:3060-41-1

Literature: Biswas, Kallolmay; Gholap, Rajesh; Srinivas, Padakanti; Kanyal, Sachin; Sarma, Koushik Das RSC Advances, 2014 , vol. 4, # 5 p. 2538 - 2545

Phenylboronic acid

CAS#:98-80-6

3-Amino-4-pheny...

CAS#:3060-41-1

Literature: RSC Advances, , vol. 4, # 5 p. 2538 - 2545

Precursor 3
CAS#:71639-13-9 3,3-diethoxycar... CAS#:1198-97-6 4-Phenyl-2-pyrr... CAS#:98-80-6 Phenylboronic acid
DownStream 3
CAS#:77472-70-9 Carphedon CAS#:67118-34-7 2-Oxo-4-phenyl-... CAS#:70291-40-6 2-Oxo-4-phenyl-...

HS Code	2922499990
Summary	HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%