NS383
Modify Date: 2024-01-14 12:07:35
NS383 structure
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Common Name | NS383 | ||
|---|---|---|---|---|
| CAS Number | 309711-59-9 | Molecular Weight | 321.37 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 583.2±50.0 °C at 760 mmHg | |
| Molecular Formula | C19H19N3O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 306.5±30.1 °C | |
Use of NS383NS383 is a potent and uniquely selective inhibitor of rat ASICs containing 1a and/or 3 subunits. NS383 inhibits H(+)-activated currents recorded from rat homomeric ASIC1a, ASIC3, and heteromeric ASIC1a+3 with IC50 values ranging from 0.61 to 2.2 μM. NS383 is well tolerated and capable of reversing pathological painlike behaviors, presumably via peripheral actions, but possibly also via actions within central pain circuits[1]. |
| Name | NS 383 |
|---|---|
| Synonym | More Synonyms |
| Description | NS383 is a potent and uniquely selective inhibitor of rat ASICs containing 1a and/or 3 subunits. NS383 inhibits H(+)-activated currents recorded from rat homomeric ASIC1a, ASIC3, and heteromeric ASIC1a+3 with IC50 values ranging from 0.61 to 2.2 μM. NS383 is well tolerated and capable of reversing pathological painlike behaviors, presumably via peripheral actions, but possibly also via actions within central pain circuits[1]. |
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| Related Catalog | |
| References |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 583.2±50.0 °C at 760 mmHg |
| Molecular Formula | C19H19N3O2 |
| Molecular Weight | 321.37 |
| Flash Point | 306.5±30.1 °C |
| Exact Mass | 321.147736 |
| LogP | 3.93 |
| Vapour Pressure | 0.0±1.7 mmHg at 25°C |
| Index of Refraction | 1.694 |
| 8-Ethyl-6,7,8,9-tetrahydro-5-phenyl-1H-pyrrolo[3,2-h]isoquinoline-2,3-dione-3-oxime |
| 1H-Pyrrolo[3,2-h]isoquinolin-2-ol, 8-ethyl-6,7,8,9-tetrahydro-3-nitroso-5-phenyl- |
| 8-Ethyl-3-nitroso-5-phenyl-6,7,8,9-tetrahydro-1H-pyrrolo[3,2-h]isoquinolin-2-ol |
- Shanghai Nianxing Industrial Co., Ltd
- China
- Product Name: NS 383
- Price: Negotiable
- Purity: 98.0%
- Delivery: 10 Day
- Contact: Huang
- Email: sales@echemcloud.com
- DC Chemicals Limited
- China
- Product Name: NS383
- Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
- Purity: 98.0%
- Delivery: 3 Day
- Contact: Tony Cao
- Email: sales@dcchemicals.com
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