Sideroxylin

Modify Date: 2024-01-09 20:05:55

Sideroxylin Structure
Sideroxylin structure
Common Name Sideroxylin
CAS Number 3122-87-0 Molecular Weight 312.317
Density 1.3±0.1 g/cm3 Boiling Point 565.5±50.0 °C at 760 mmHg
Molecular Formula C18H16O5 Melting Point N/A
MSDS N/A Flash Point 210.3±23.6 °C

 Use of Sideroxylin


Sideroxylin is a C-methylated flavone isolated from Callistemon lanceolatus and exerts antimicrobial activity against Staphylococcus aureus. Sideroxylin inhibits ovarian cancer cell proliferation and induces apoptosis, causing DNA fragmentation, depolarization of the mitochondrial membrane, the generation of reactive oxygen species (ROS)[1].

 Names

Name 5-hydroxy-2-(4-hydroxyphenyl)-7-methoxy-6,8-dimethylchromen-4-one
Synonym More Synonyms

 Sideroxylin Biological Activity

Description Sideroxylin is a C-methylated flavone isolated from Callistemon lanceolatus and exerts antimicrobial activity against Staphylococcus aureus. Sideroxylin inhibits ovarian cancer cell proliferation and induces apoptosis, causing DNA fragmentation, depolarization of the mitochondrial membrane, the generation of reactive oxygen species (ROS)[1].
Related Catalog
References

[1]. Sunwoo Park, et al. Sideroxylin (Callistemon Lanceolatus) Suppressed Cell Proliferation and Increased Apoptosis in Ovarian Cancer Cells Accompanied by Mitochondrial Dysfunction, the Generation of Reactive Oxygen Species, and an Increase of Lipid Peroxidation. J Cell Physiol. 2018 Nov;233(11):8597-8604.

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 565.5±50.0 °C at 760 mmHg
Molecular Formula C18H16O5
Molecular Weight 312.317
Flash Point 210.3±23.6 °C
Exact Mass 312.099762
PSA 79.90000
LogP 3.28
Vapour Pressure 0.0±1.6 mmHg at 25°C
Index of Refraction 1.644

 Safety Information

Hazard Codes Xi
HS Code 2914509090

 Customs

HS Code 2914509090
Summary HS:2914509090 other ketones with other oxygen function VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

 Synonyms

4',5-Dihydroxy-7-methoxy-6,8-dimethylflavone
5-Hydroxy-2-(4-hydroxyphenyl)-7-methoxy-6,8-dimethyl-4H-chromen-4-one
4H-1-Benzopyran-4-one, 5-hydroxy-2-(4-hydroxyphenyl)-7-methoxy-6,8-dimethyl-
5,4'-dihydroxy-7-methoxy-6,8-dimethylflavone
sideroxyline
5-Hydroxy-2-(4-hydroxyphenyl)-7-methoxy-6,8-dimethyl-4H-1-benzopyran-4-one
sideroxylin
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