2-Hydroxy-6-methoxybenzoic acid

Modify Date: 2024-01-08 05:40:17

2-Hydroxy-6-methoxybenzoic acid structure	Common Name	2-Hydroxy-6-methoxybenzoic acid
	CAS Number	3147-64-6	Molecular Weight	168.147
	Density	1.4±0.1 g/cm3	Boiling Point	330.4±27.0 °C at 760 mmHg
	Molecular Formula	C₈H₈O₄	Melting Point	134-138
	MSDS	Chinese USA	Flash Point	138.7±17.2 °C
	Symbol	GHS07	Signal Word	Warning

Use of 2-Hydroxy-6-methoxybenzoic acid

2-Hydroxy-6-methoxybenzoic acid can be used for the determination of acetylsalicylic acid and its major metabolite, salicylic acid, in animal plasma. 2-Hydroxy-6-methoxybenzoic acid exhibits significant analgesic effects[1][2].

Name	2-hydroxy-6-methoxybenzoic acid
Synonym	More Synonyms

Description	2-Hydroxy-6-methoxybenzoic acid can be used for the determination of acetylsalicylic acid and its major metabolite, salicylic acid, in animal plasma. 2-Hydroxy-6-methoxybenzoic acid exhibits significant analgesic effects[1][2].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Neurological Disease
References	[1]. Xu X, et al. Rapid and sensitive determination of acetylsalicylic acid and salicylic acid in plasma using liquid chromatography-tandem mass spectrometry: application to pharmacokinetic study. Biomed Chromatogr. 2009 Sep;23(9):973-9. [2]. Palacios-Espinosa F, et al. Antinociceptive, hypoglycemic and spasmolytic effects of Brickellia veronicifolia. J Ethnopharmacol. 2008 Aug 13;118(3):448-54.

Description

Related Catalog

Signaling Pathways >> Others >> Others

Research Areas >> Neurological Disease

References

[1]. Xu X, et al. Rapid and sensitive determination of acetylsalicylic acid and salicylic acid in plasma using liquid chromatography-tandem mass spectrometry: application to pharmacokinetic study. Biomed Chromatogr. 2009 Sep;23(9):973-9.

[2]. Palacios-Espinosa F, et al. Antinociceptive, hypoglycemic and spasmolytic effects of Brickellia veronicifolia. J Ethnopharmacol. 2008 Aug 13;118(3):448-54.

Density	1.4±0.1 g/cm3
Boiling Point	330.4±27.0 °C at 760 mmHg
Melting Point	134-138
Molecular Formula	C₈H₈O₄
Molecular Weight	168.147
Flash Point	138.7±17.2 °C
Exact Mass	168.042252
PSA	66.76000
LogP	1.78
Vapour Pressure	0.0±0.8 mmHg at 25°C
Index of Refraction	1.586

2-Hydroxy-6-methoxybenzoic acid MSDS(Chinese)

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H315-H319-H335
Precautionary Statements	P261-P305 + P351 + P338
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xi: Irritant;
Risk Phrases	R36/37/38
Safety Phrases	S26-S36
RIDADR	NONH for all modes of transport
HS Code	2918990090

Tetrahydropyran...

CAS#:30778-86-0

Carbon dioxide

CAS#:124-38-9

~72%

2-Hydroxy-6-met...

CAS#:3147-64-6

Literature: Kuehnert, Sven M; Maier, Martin E Organic letters, 2002 , vol. 4, # 4 p. 643 - 646

2,6-Dimethoxybe...

CAS#:1466-76-8

~60%

2-Hydroxy-6-met...

CAS#:3147-64-6

Literature: Kung; Kasliwal; Pan; Mach; Guo Journal of Medicinal Chemistry, 1988 , vol. 31, # 5 p. 1039 - 1043

Methyl 2,6-Dime...

CAS#:2065-27-2

~35%

2-Hydroxy-6-met...

CAS#:3147-64-6

Literature: Lamotte; Demerseman; Royer; et al. European Journal of Medicinal Chemistry, 1986 , vol. 21, # 5 p. 379 - 383

2,6-Dihydroxybe...

CAS#:303-07-1

Dimethyl sulfate

CAS#:77-78-1

2-Hydroxy-6-met...

CAS#:3147-64-6

Literature: Journal of the American Chemical Society, , vol. 93, p. 3237 - 3248

1-(2-Hydroxy-6-...

CAS#:703-23-1

2-Hydroxy-6-met...

CAS#:3147-64-6

Literature: Journal of the Chemical Society, , p. 2434,2439

Precursor 6
CAS#:124-38-9 Carbon dioxide CAS#:1466-76-8 2,6-Dimethoxybe... CAS#:2065-27-2 Methyl 2,6-Dime... CAS#:303-07-1 2,6-Dihydroxybe...
CAS#:77-78-1 Dimethyl sulfate CAS#:703-23-1 1-(2-Hydroxy-6-...
DownStream 8
CAS#:145645-18-7 methyl 2-methox... CAS#:22833-69-8 methyl 2-hydrox... CAS#:84226-06-2 IBZM CAS#:325172-28-9 2-methoxy-6-pro...
CAS#:2065-27-2 Methyl 2,6-Dime... CAS#:113452-76-9 2-Hydroxy-3-iod... CAS#:921207-63-8 methyl 2-etheny... CAS#:6052-93-3 1,3,8-Trihydrox...

HS Code	2918990090
Summary	2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Molecularly imprinted polymers with synthetic dummy template for simultaneously selective removal and enrichment of ginkgolic acids from Ginkgo biloba L. leaves extracts.

J. Chromatogr. A. 1368 , 44-51, (2014)

Dummy molecularly imprinted polymers (DMIPs) for simultaneously selective removal and enrichment of ginkgolic acids (GAs) during the processing of Ginkgo biloba leaves have been prepared. Two dummy te...

Rapid and sensitive determination of acetylsalicylic acid and salicylic acid in plasma using liquid chromatography-tandem mass spectrometry: application to pharmacokinetic study.

Biomed. Chromatogr. 23(9) , 973-9, (2009)

A simple and sensitive analytical method using liquid chromatography-tandem mass spectrometry (LC/MS/MS) for determination of acetylsalicylic acid (aspirin, ASA) and its major metabolite, salicylic ac...

Antinociceptive, hypoglycemic and spasmolytic effects ofBrickellia veronicifolia

J. Ethnopharmacol. 118(3) , 448-54, (2008)

Introduction Brickellia veronicifolia (Kunth) Gray (Asteraceae) (BV) is broadly commercialized for treating gastrointestinal diseases (stomach aches, biliary colics and dyspepsia), arthritis, diabetes...

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