JNJ-2408068

Modify Date: 2024-01-27 10:47:33

JNJ-2408068 Structure
JNJ-2408068 structure
Common Name JNJ-2408068
CAS Number 317846-22-3 Molecular Weight 394.51300
Density N/A Boiling Point N/A
Molecular Formula C22H30N6O Melting Point N/A
MSDS N/A Flash Point N/A

 Use of JNJ-2408068


JNJ 2408068 is a potent RSV (respiratory syncytial virus) inhibitor. JNJ 2408068 significantly inhibits replication of RSV A and B subtypes in the lungs of cotton rats without any evidence of toxicity. The minimum protective dose of JNJ 2408068 appears to be approximately 0.39 mg/kg[1].

 Names

Name 2-[[2-[[1-(2-aminoethyl)piperidin-4-yl]amino]-4-methylbenzimidazol-1-yl]methyl]-6-methylpyridin-3-ol
Synonym More Synonyms

 JNJ-2408068 Biological Activity

Description JNJ 2408068 is a potent RSV (respiratory syncytial virus) inhibitor. JNJ 2408068 significantly inhibits replication of RSV A and B subtypes in the lungs of cotton rats without any evidence of toxicity. The minimum protective dose of JNJ 2408068 appears to be approximately 0.39 mg/kg[1].
Related Catalog
Target

RSV-A

RSV-B

References

[1]. Wyde PR, et al. Short duration aerosols of JNJ 2408068 (R170591) administered prophylactically or therapeutically protect cotton rats from experimental respiratory syncytial virus infection. Antiviral Res. 2003 Nov;60(3):221-31.

 Chemical & Physical Properties

Molecular Formula C22H30N6O
Molecular Weight 394.51300
Exact Mass 394.24800
PSA 95.46000
LogP 2.69710

 Synonyms

unii-ab821dl88a
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