SSR 125543A

Modify Date: 2024-01-12 15:34:18

SSR 125543A Structure
SSR 125543A structure
Common Name SSR 125543A
CAS Number 321839-75-2 Molecular Weight 519.501
Density N/A Boiling Point N/A
Molecular Formula C27H29Cl2FN2OS Melting Point N/A
MSDS N/A Flash Point N/A

 Use of SSR 125543A


Crinecerfont (SSR-125543) hydrochloride is a potent, orally active, non-peptide CRF1 receptor antagonist. Crinecerfont can be used for Classic congenital adrenal hyperplasia (CAH) research[1].

 Names

Name 4-(2-Chloro-4-methoxy-5-methylphenyl)-N-[(1S)-2-cyclopropyl-1-(3-fluoro-4-methylphenyl)ethyl]-5-methyl-N-(2-propyn-1-yl)-1,3-thiazol-2-amine hydrochloride (1:1)
Synonym More Synonyms

 SSR 125543A Biological Activity

Description Crinecerfont (SSR-125543) hydrochloride is a potent, orally active, non-peptide CRF1 receptor antagonist. Crinecerfont can be used for Classic congenital adrenal hyperplasia (CAH) research[1].
Related Catalog
Target

IC50: CRF1 receptor

References

[1]. Global Safety and Efficacy Registration Study of Crinecerfont for Congenital Adrenal Hyperplasia (CAHtalyst).

 Chemical & Physical Properties

Molecular Formula C27H29Cl2FN2OS
Molecular Weight 519.501
Exact Mass 518.136169

 Synonyms

2-Thiazolamine, 4-(2-chloro-4-methoxy-5-methylphenyl)-N-[(1S)-2-cyclopropyl-1-(3-fluoro-4-methylphenyl)ethyl]-5-methyl-N-2-propyn-1-yl-, hydrochloride (1:1)
4-(2-Chloro-4-methoxy-5-methylphenyl)-N-[(1S)-2-cyclopropyl-1-(3-fluoro-4-methylphenyl)ethyl]-5-methyl-N-(2-propyn-1-yl)-1,3-thiazol-2-amine hydrochloride (1:1)
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