Sabiporide hydrochloride

Modify Date: 2024-02-08 11:14:42

Sabiporide hydrochloride structure	Common Name	Sabiporide hydrochloride
	CAS Number	324758-66-9	Molecular Weight	408.37800
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₈H₁₉F₃N₆O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Sabiporide hydrochloride

Sabiporide hydrochloride is a NHE-1 inhibitor (Ki: 50 nM). Sabiporide hydrochloride has cardioprotective and neuroprotective effects. Sabiporide hydrochloride inhibits glutamate- or NMDA-induced neuronal cell death[1][2].

Name	N-(diaminomethylidene)-4-[4-(1H-pyrrole-2-carbonyl)piperazin-1-yl]-3-(trifluoromethyl)benzamide
Synonym	More Synonyms

Description	Sabiporide hydrochloride is a NHE-1 inhibitor (Ki: 50 nM). Sabiporide hydrochloride has cardioprotective and neuroprotective effects. Sabiporide hydrochloride inhibits glutamate- or NMDA-induced neuronal cell death[1][2].
Related Catalog	Research Areas >> Cardiovascular Disease Research Areas >> Neurological Disease
References	[1]. Touret N, et al. Characterization of sabiporide, a new specific NHE-1 inhibitor exhibiting slow dissociation kinetics and cardioprotective effects. Eur J Pharmacol. 2003 Jan 17;459(2-3):151-8. [2]. Park HS, et al. Effects of sabiporide, a specific Na+/H+ exchanger inhibitor, on neuronal cell death and brain ischemia. Brain Res. 2005 Nov 2;1061(1):67-71.

Description

Related Catalog

Research Areas >> Cardiovascular Disease

Research Areas >> Neurological Disease

References

[1]. Touret N, et al. Characterization of sabiporide, a new specific NHE-1 inhibitor exhibiting slow dissociation kinetics and cardioprotective effects. Eur J Pharmacol. 2003 Jan 17;459(2-3):151-8.

[2]. Park HS, et al. Effects of sabiporide, a specific Na+/H+ exchanger inhibitor, on neuronal cell death and brain ischemia. Brain Res. 2005 Nov 2;1061(1):67-71.

Molecular Formula	C₁₈H₁₉F₃N₆O₂
Molecular Weight	408.37800
Exact Mass	408.15200
PSA	121.80000
LogP	2.99690

Sabiporide

UNII-U52APA00X7

Sabiporide HCl

Sabiporide hydrochloride

Use of Sabiporide hydrochloride

Names

Sabiporide hydrochloride Biological Activity

Chemical & Physical Properties

Synonyms