(2R)-2,3-Bis[(2H27)tetradecanoyloxy]propyl 2-{tris[(2H3)methyl]ammonio}(2H4)ethyl phosphate

Modify Date: 2024-02-25 17:06:20

(2R)-2,3-Bis[(2H27)tetradecanoyloxy]propyl 2-{tris[(2H3)methyl]ammonio}(2H4)ethyl phosphate Structure
(2R)-2,3-Bis[(2H27)tetradecanoyloxy]propyl 2-{tris[(2H3)methyl]ammonio}(2H4)ethyl phosphate structure
Common Name (2R)-2,3-Bis[(2H27)tetradecanoyloxy]propyl 2-{tris[(2H3)methyl]ammonio}(2H4)ethyl phosphate
CAS Number 326495-32-3 Molecular Weight 745.345
Density N/A Boiling Point N/A
Molecular Formula C36H5D67NO8P Melting Point N/A
MSDS N/A Flash Point N/A

 Use of (2R)-2,3-Bis[(2H27)tetradecanoyloxy]propyl 2-{tris[(2H3)methyl]ammonio}(2H4)ethyl phosphate


1,2-Dimyristoyl-sn-glycero-3-phosphocholine-d67 is deuterium labeled 1,2-Dimyristoyl-sn-glycero-3-phosphocholine. 1,2-Dimyristoyl-sn-glycero-3-phosphocholine (DMPC) is a synthetic phospholipid used in liposomes. 1,2-Dimyristoyl-sn-glycero-3-phosphocholine

 Names

Name (2R)-2,3-Bis[(2H27)tetradecanoyloxy]propyl 2-{tris[(2H3)methyl]ammonio}(2H4)ethyl phosphate
Synonym More Synonyms

  Biological Activity

Description 1,2-Dimyristoyl-sn-glycero-3-phosphocholine-d67 is deuterium labeled 1,2-Dimyristoyl-sn-glycero-3-phosphocholine. 1,2-Dimyristoyl-sn-glycero-3-phosphocholine (DMPC) is a synthetic phospholipid used in liposomes. 1,2-Dimyristoyl-sn-glycero-3-phosphocholine
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[2].
References

[1]. Iwona Budziak, et al. Effect of polyols on the DMPC lipid monolayers and bilayers. Biochim Biophys Acta Biomembr. 2018 Nov;1860(11):2166-2174.

[2]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-223.

 Chemical & Physical Properties

Molecular Formula C36H5D67NO8P
Molecular Weight 745.345
Exact Mass 744.920105
LogP 8.75

 Synonyms

(2R)-2,3-Bis[(H)tetradecanoyloxy]propyl 2-{tris[(H)methyl]ammonio}(H)ethyl phosphate
Ethan-1,1,2,2-d-aminium, 2-[[[(2R)-2,3-bis[(1-oxotetradecyl-2,2,3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,11,11,12,12,13,13,14,14,14-d)oxy]propoxy]hydroxyphosphinyl]oxy]-N,N,N-tri(methyl-d)-, inner ;salt