4-Trifluoromethylsalicylic acid

Modify Date: 2024-01-02 10:25:29

4-Trifluoromethylsalicylic acid Structure
4-Trifluoromethylsalicylic acid structure
Common Name 4-Trifluoromethylsalicylic acid
CAS Number 328-90-5 Molecular Weight 206.119
Density 1.5±0.1 g/cm3 Boiling Point 286.4±40.0 °C at 760 mmHg
Molecular Formula C8H5F3O3 Melting Point 178ºC
MSDS USA Flash Point 127.0±27.3 °C

 Use of 4-Trifluoromethylsalicylic acid


4-Trifluoromethylsalicylic acid (Desacetyl triflusal) is a platelet aggregation inhibitor[1].

 Names

Name 2-Hydroxy-4-(trifluoromethyl)benzoic acid
Synonym More Synonyms

 4-Trifluoromethylsalicylic acid Biological Activity

Description 4-Trifluoromethylsalicylic acid (Desacetyl triflusal) is a platelet aggregation inhibitor[1].
Related Catalog
References

[1]. Rodríguez G, et al. Hydrophilic polymer drug from a derivative of salicylic acid: synthesis, controlled release studies and biological behavior. Macromol Biosci. 2004;4(6):579-586.

 Chemical & Physical Properties

Density 1.5±0.1 g/cm3
Boiling Point 286.4±40.0 °C at 760 mmHg
Melting Point 178ºC
Molecular Formula C8H5F3O3
Molecular Weight 206.119
Flash Point 127.0±27.3 °C
Exact Mass 206.019073
PSA 57.53000
LogP 4.16
Vapour Pressure 0.0±0.6 mmHg at 25°C
Index of Refraction 1.510

 Safety Information

Hazard Codes Xi: Irritant;
Risk Phrases R36/37/38
Safety Phrases 26-36/37/39
HS Code 2918290000

 Synthetic Route

 Customs

HS Code 2918290000
Summary HS: 2918290000 other carboxylic acids with phenol function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) VAT:17.0% MFN tariff:6.5% General tariff:30.0%

 Articles23

More Articles
The study of the influence of surfactant charge on alkaline hydrolysis reactions of acetylsalicylic acid (ASA) and triflusal (TFL) using spectrophotometric methods.

Eur. J. Pharm. Sci. 31(3-4) , 211-20, (2007)

In this research, the effects of micellar systems on alkaline hydrolysis reactions of acetylsalicylic acid (ASA) and triflusal (TFL) were found to be dependant upon the surfactant charge within the mi...

A phase I study to characterize the multiple-dose pharmacokinetics, pharmacodynamics and safety of new enteric-coated triflusal formulations in healthy male volunteers.

Expert Opin. Drug Metab. Toxicol. 7(12) , 1471-9, (2011)

An enteric-coated formulation of triflusal (triflusal EC), an antiplatelet agent, was developed to reduce the high incidence of gastrointestinal adverse events (AEs). The aim of this study is to compa...

Salicylates increase insulin secretion in healthy obese subjects.

J. Clin. Endocrinol. Metab. 93(7) , 2523-30, (2008)

Conflicting results on the effects of salicylates on glucose tolerance in subjects with normal glucose tolerance or type 2 diabetes have been reported.The objective of the study was to investigate the...

 Synonyms

Benzoic acid, 2-hydroxy-4-(trifluoromethyl)-
QVR BQ DXFFF
2-Hydroxy-4-(trifluoromethyl)benzoic acid
MFCD01529657
4-Trifluoromethylsalicylic acid
4-Trifluoromethyl Salicylic Acid
2-hydroxy-4-trifluoromethyl benzoic acid
Triflusal impurity B
4-(TrifluoroMethyl)salicylic Acid
4-Tfmsa
Top Suppliers:I want be here




Get all suppliers and price by the below link:

4-Trifluoromethylsalicylic acid suppliers

4-Trifluoromethylsalicylic acid price