Cajanin
Modify Date: 2024-01-10 20:17:47
Cajanin structure
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Common Name | Cajanin | ||
|---|---|---|---|---|
| CAS Number | 32884-36-9 | Molecular Weight | 300.263 | |
| Density | 1.5±0.1 g/cm3 | Boiling Point | 605.5±55.0 °C at 760 mmHg | |
| Molecular Formula | C16H12O6 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 231.7±25.0 °C | |
Use of CajaninCajanin is a potent and orally active anti-melanogenic agent. Cajanin shows antiproliferative activity in MNT1 Cells. Cajanin efficiently decreases the melanin content. Cajanin down-regulates the mRNA and protein expression levels of MITF, tyrosinase, TRP-1 and Dct (TRP-2). Cajanin induces cell cycle arrest at G2/M and S phase. Cajanin stimulates osteoblast proliferation. Cajanin has the potential for the research of human hyperpigmented disorders and menopausal osteoporosis[1][2]. |
| Name | 3-(2,4-dihydroxyphenyl)-5-hydroxy-7-methoxychromen-4-one |
|---|---|
| Synonym | More Synonyms |
| Description | Cajanin is a potent and orally active anti-melanogenic agent. Cajanin shows antiproliferative activity in MNT1 Cells. Cajanin efficiently decreases the melanin content. Cajanin down-regulates the mRNA and protein expression levels of MITF, tyrosinase, TRP-1 and Dct (TRP-2). Cajanin induces cell cycle arrest at G2/M and S phase. Cajanin stimulates osteoblast proliferation. Cajanin has the potential for the research of human hyperpigmented disorders and menopausal osteoporosis[1][2]. |
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| Related Catalog | |
| In Vitro | Cajanin shows strong mitogenic as well as differentiation-promoting effects on osteoblasts[2]. Cajanin induces the phosphorylation of both Erk1/2 and Akt[2]. |
| In Vivo | Cajanin (10 mg/kg, p.o.; daily for 30 consecutive days) increases the BMD levels in all anatomical regions of the skeleton studied in Sprague Dawley rats[1]. |
| References |
| Density | 1.5±0.1 g/cm3 |
|---|---|
| Boiling Point | 605.5±55.0 °C at 760 mmHg |
| Molecular Formula | C16H12O6 |
| Molecular Weight | 300.263 |
| Flash Point | 231.7±25.0 °C |
| Exact Mass | 300.063385 |
| PSA | 100.13000 |
| LogP | 3.57 |
| Vapour Pressure | 0.0±1.8 mmHg at 25°C |
| Index of Refraction | 1.697 |
| Hazard Codes | Xi |
|---|---|
| HS Code | 2914509090 |
CAS#:98094-87-2| HS Code | 2914509090 |
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| Summary | HS:2914509090 other ketones with other oxygen function VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0% |
| 5,2',4'-Trihydroxy-7-methoxyisoflavone |
| Cajanin |
| 2',4',5-Trihydroxy-7-methoxyisoflavon |
| 4H-1-Benzopyran-4-one, 3-(2,4-dihydroxyphenyl)-5-hydroxy-7-methoxy- |
| 3-(2,4-Dihydroxyphenyl)-5-hydroxy-7-methoxy-4H-chromen-4-one |
| 2',4',5-trihydroxy-7-methoxyisoflavone |