(Z)-Thiothixene

Modify Date: 2024-01-03 11:16:16

(Z)-Thiothixene structure	Common Name	(Z)-Thiothixene
	CAS Number	3313-26-6	Molecular Weight	443.62500
	Density	1.269 g/cm3	Boiling Point	599ºC at 760 mmHg
	Molecular Formula	C₂₃H₂₉N₃O₂S₂	Melting Point	114-118ºC
	MSDS	N/A	Flash Point	316.1ºC
	Symbol	GHS07	Signal Word	Warning

Use of (Z)-Thiothixene

(Z)-Thiothixene is an antagonist of serotonergic receptor extracted from patent US 20150141345 A1.

Name	cis-Thiothixene N,N-Dimethyl-9-[3-(4-methyl-1-piperazinyl)propylidene]thioxanthene-2-sulfonamide
Synonym	More Synonyms

Description	(Z)-Thiothixene is an antagonist of serotonergic receptor extracted from patent US 20150141345 A1.
Related Catalog	Signaling Pathways >> GPCR/G Protein >> 5-HT Receptor Signaling Pathways >> Neuronal Signaling >> 5-HT Receptor Research Areas >> Neurological Disease
Target	serotonergic receptor[1]
In Vitro	(Z)-Thiothixene is capable of promoting cell survival and/or plasticity, and/or inhibiting cell death, especially when a toxic agent is exposed to the cells, including neuronal cells[1]. (Z)-Thiothixene is a Z (cis) isomer of thiothixene, as well as synthetic precursor and degradant[2].
References	[1]. Illana Gozes, et al. Novel compounds and methods for inhibiting cell death. US 20150141345 A1. [2]. Severin G. Comprehensive high-performance liquid chromatographic methodology for the determination of thiothixene in bulk drug, finished product, and dissolution testing samples. J Pharm Sci. 1987 Mar;76(3):231-4.

Density	1.269 g/cm3
Boiling Point	599ºC at 760 mmHg
Melting Point	114-118ºC
Molecular Formula	C₂₃H₂₉N₃O₂S₂
Molecular Weight	443.62500
Flash Point	316.1ºC
Exact Mass	443.17000
PSA	77.54000
LogP	4.42730
Index of Refraction	1.643
Storage condition	2-8°C

(Z)-Thiothixene MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: XO1420000

CHEMICAL NAME :: Thioxanthene-2-sulfonamide, N,N-dimethyl-9-(3-(4-methyl-1-piperazinyl)propylidene )-, (Z)-

CAS REGISTRY NUMBER :: 3313-26-6

LAST UPDATED :: 199712

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C23-H29-N3-O2-S2

MOLECULAR WEIGHT :: 443.67

WISWESSER LINE NOTATION :: T C666 BS IYJ FSWN1&1 IU3- AT6N DNTJ D1 -C

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 55 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PSYPAG Psychopharmacologia (Berlin). (Berlin, Ger.) V.1-46, 1959-76. For publisher information, see PSCHDL. Volume(issue)/page/year: 12,142,1968

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 100 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 13,17,1970

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H302
Precautionary Statements	P301 + P312 + P330
Hazard Codes	Xn: Harmful;
Risk Phrases	R22
RIDADR	NONH for all modes of transport
RTECS	XO1420000

Thiothixene

MFCD00079574

N,N-Dimethyl-9-[3-(4-methyl-1-piperazinyl)propylidene]thioxanthene-2-sulfonamide

cis-Thiothixene

(Z)-Thiothixene

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: (Z)-Thiothixene
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Purity: 98.0%
Delivery: 10 Day
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Henan Tianfu Chemical Co., Ltd.
China
Product Name: cis-Thiothixene N,N-Dimethyl-9-[3-(4-methyl-1-piperazinyl)propylidene]thioxanthene-2-sulfonamide
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Delivery: Inquiry
Contact: Anson
Email: info@tianfuchem.com

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(Z)-Thiothixene

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(Z)-Thiothixene Biological Activity

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MSDS

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CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

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