gliquidone

Modify Date: 2024-01-02 23:30:51

gliquidone Structure
gliquidone structure
Common Name gliquidone
CAS Number 33342-05-1 Molecular Weight 527.632
Density 1.3±0.1 g/cm3 Boiling Point N/A
Molecular Formula C27H33N3O6S Melting Point 179ºC
MSDS N/A Flash Point N/A

 Use of gliquidone


Gliquidone (AR-DF 26) is an anti-diabetic drug in the sulfonylurea class, used in the treatment of diabetes mellitus type 2.

 Names

Name 1-cyclohexyl-3-[4-[2-(7-methoxy-4,4-dimethyl-1,3-dioxoisoquinolin-2-yl)ethyl]phenyl]sulfonylurea
Synonym More Synonyms

 gliquidone Biological Activity

Description Gliquidone (AR-DF 26) is an anti-diabetic drug in the sulfonylurea class, used in the treatment of diabetes mellitus type 2.
Related Catalog

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Melting Point 179ºC
Molecular Formula C27H33N3O6S
Molecular Weight 527.632
Exact Mass 527.208984
PSA 130.26000
LogP 3.11
Index of Refraction 1.624
Storage condition 2-8C

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
DB1584250
CHEMICAL NAME :
Benzenesulfonamide, N-((cyclohexylamino)carbonyl)-4-(2-(3,4-dihydro-7-met hoxy-4,4-dimethyl- 1,3-dioxo-2(1H)-isoquinolinyl)ethyl)-
CAS REGISTRY NUMBER :
33342-05-1
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C27-H33-N3-O6-S
MOLECULAR WEIGHT :
527.69

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
450 mg/kg
SEX/DURATION :
female 8-16 day(s) after conception
TOXIC EFFECTS :
Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) Reproductive - Effects on Embryo or Fetus - other effects to embryo
REFERENCE :
OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 11,119,1976

 Safety Information

RTECS DB1584250

 Synonyms

Gliquidonum
Glurenorm
Beglynora
EINECS 251-463-2
gliquidone
N-[(cyclohexylamino)carbonyl]-4-{2-[4,4-dimethyl-7-(methyloxy)-1,3-dioxo-3,4-dihydroisoquinolin-2(1H)-yl]ethyl}benzenesulfonamide
Benzenesulfonamide, N-[(cyclohexylamino)carbonyl]-4-[2-(3,4-dihydro-7-methoxy-4,4-dimethyl-1,3-dioxo-2(1H)-isoquinolinyl)ethyl]-
Gliquidona
Beglynor
N-(Cyclohexylcarbamoyl)-4-[2-(7-methoxy-4,4-dimethyl-1,3-dioxo-3,4-dihydro-2(1H)-isoquinolinyl)ethyl]benzenesulfonamide
glikvidon
N-(Cyclohexylcarbamoyl)-4-[2-(7-methoxy-4,4-dimethyl-1,3-dioxo-3,4-dihydroisoquinolin-2(1H)-yl)ethyl]benzenesulfonamide
glycvidon
MFCD00631870
N-(Cyclohexylcarbamoyl)-4-[2-(7-methoxy-4,4-dimethyl-1,3-dioxo-3,4-dihydroisochinolin-2(1H)-yl)ethyl]benzolsulfonamid
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Price: $66/10mM*1mLinDMSO

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