N-[5-(2-methoxyethoxy)-2-pyrimidinyl]benzenesulphonamide

Modify Date: 2024-01-16 12:28:45

N-[5-(2-methoxyethoxy)-2-pyrimidinyl]benzenesulphonamide Structure
N-[5-(2-methoxyethoxy)-2-pyrimidinyl]benzenesulphonamide structure
 Common Name N-[5-(2-methoxyethoxy)-2-pyrimidinyl]benzenesulphonamide
CAS Number 339-44-6 Molecular Weight 309.34100
Density 1.354g/cm3 Boiling Point 515.1ºC at 760mmHg
Molecular Formula C13H15N3O4S Melting Point N/A
MSDS N/A Flash Point 265.4ºC

 Use of N-[5-(2-methoxyethoxy)-2-pyrimidinyl]benzenesulphonamide


Glymidine (Glidiazine) is a hypoglycaemic agent. Glymidine is a lipid soluble sulphapyrimidine derivative. Glymidine appears to stimulate insulin release from pancreas. Glymidine is a possible alternative to the sulphonylureas and biguanides for the research of diabetes mellitus[1].

 Names

Name N-[5-(2-methoxyethoxy)pyrimidin-2-yl]benzenesulfonamide
Synonym More Synonyms

  Biological Activity

Description Glymidine (Glidiazine) is a hypoglycaemic agent. Glymidine is a lipid soluble sulphapyrimidine derivative. Glymidine appears to stimulate insulin release from pancreas. Glymidine is a possible alternative to the sulphonylureas and biguanides for the research of diabetes mellitus[1].
Related Catalog
References

[1]. Glymidine. Br Med J. 1967;2(5555):817.

 Chemical & Physical Properties

Density 1.354g/cm3
Boiling Point 515.1ºC at 760mmHg
Molecular Formula C13H15N3O4S
Molecular Weight 309.34100
Flash Point 265.4ºC
Exact Mass 309.07800
PSA 98.79000
LogP 2.45640
Index of Refraction 1.588

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
DB2910000
CHEMICAL NAME :
Benzenesulfonamide, N-(5-(2-methoxyethoxy)-2-pyrimidinyl)-
CAS REGISTRY NUMBER :
339-44-6
BEILSTEIN REFERENCE NO. :
0552655
LAST UPDATED :
199709
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C13-H15-N3-O4-S
MOLECULAR WEIGHT :
309.37
WISWESSER LINE NOTATION :
T6N CNJ BMSWR& EO201

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
3100 mg/kg
TOXIC EFFECTS :
Endocrine - hypoglycemia
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 14,377,1964

 Safety Information

HS Code 2935009090

 Customs

HS Code 2935009090
Summary 2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0%

 Synonyms

Glycodiazin
Glycodiazin [German]
EINECS 206-426-5
N-[5-(2-methoxy-ethoxy)-pyrimidin-2-yl]-benzenesulfonamide
GLYMIDINE
UNII-4C5I4BQZ8F
Glymidinum
Glycodiazine
Glidiazine
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Chemsrc provides CAS#:339-44-6 MSDS, density, melting point, boiling point, structure, etc. Its name is N-[5-(2-methoxyethoxy)-2-pyrimidinyl]benzenesulphonamide>> amp version: N-[5-(2-methoxyethoxy)-2-pyrimidinyl]benzenesulphonamide

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