PNU-248686A

Modify Date: 2024-09-14 16:21:26

PNU-248686A Structure
PNU-248686A structure
Common Name PNU-248686A
CAS Number 341498-89-3 Molecular Weight 485.96
Density N/A Boiling Point N/A
Molecular Formula C22H19ClNaO5S2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of PNU-248686A


PNU-248686A is a novel matrix metalloproteinase (MMP) inhibitor.

 Names

Name PNU-248686A
Synonym More Synonyms

 PNU-248686A Biological Activity

Description PNU-248686A is a novel matrix metalloproteinase (MMP) inhibitor.
Related Catalog
Target

MMP[1]

In Vitro PNU-248686A is an orally active matrix metalloproteinase (MMP) inhibitor developed for the treatment of solid tumors over-expressing MMPs[1].
References

[1]. Frigerio E, et al. Determination of PNU-248686A, a novel matrix metalloproteinase inhibitor, in human plasma by liquid chromatography-tandem mass spectrometry, following protein precipitation in the 96-well plate format. J Chromatogr A. 2003 Feb 14;987(1-2):249-56.

 Chemical & Physical Properties

Molecular Formula C22H19ClNaO5S2
Molecular Weight 485.96
Storage condition 2-8℃

 Synonyms

Sodium (2R)-3-[(4'-chloro-4-biphenylyl)sulfonyl]-2-hydroxy-2-[(phenylsulfanyl)methyl]propanoate
Propanoic acid, 3-[(4'-chloro[1,1'-biphenyl]-4-yl)sulfonyl]-2-hydroxy-2-[(phenylthio)methyl]-, sodium salt, (2R)- (1:1)