Arnicolide D

Modify Date: 2024-01-12 17:48:15

Arnicolide D Structure
Arnicolide D structure
Common Name Arnicolide D
CAS Number 34532-68-8 Molecular Weight 332.39100
Density N/A Boiling Point N/A
Molecular Formula C19H24O5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Arnicolide D


Arnicolide D is a sesquiterpene lactone isolated from Centipeda minima. Arnicolide D modulates the cell cycle, activates the caspase signaling pathway and inhibits the PI3K/AKT/mTOR and STAT3 signaling pathways. Arnicolide D inhibits Nasopharyngeal carcinoma (NPC) cell viability in a concentration- and time-dependent manner[1].

 Names

Name [(1S,3aR,5R,5aR,8aR,9S,9aR)-1,5,8a-trimethyl-2,8-dioxo-3a,4,5,5a,9,9a-hexahydro-1H-azuleno[6,5-b]furan-9-yl] 2-methylprop-2-enoate
Synonym More Synonyms

 Arnicolide D Biological Activity

Description Arnicolide D is a sesquiterpene lactone isolated from Centipeda minima. Arnicolide D modulates the cell cycle, activates the caspase signaling pathway and inhibits the PI3K/AKT/mTOR and STAT3 signaling pathways. Arnicolide D inhibits Nasopharyngeal carcinoma (NPC) cell viability in a concentration- and time-dependent manner[1].
Related Catalog
Target

Caspase

PI3K

Akt

mTOR

STAT3

References

[1]. Liu R, et al. Arnicolide D, from the herb Centipeda minima, Is a Therapeutic Candidate against Nasopharyngeal Carcinoma. Molecules. 2019 May 17;24(10).

 Chemical & Physical Properties

Molecular Formula C19H24O5
Molecular Weight 332.39100
Exact Mass 332.16200
PSA 69.67000
LogP 2.45320

 Synonyms

11alpha,13-dihydrohelenalinmethacrylate
11,13-Dihydrohelenalin methacrylate
Arnicolide D
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