7α-Hydroxycholesterol-d7

Modify Date: 2024-01-24 12:24:57

7α-Hydroxycholesterol-d7 structure	Common Name	7α-Hydroxycholesterol-d7
	CAS Number	349553-94-2	Molecular Weight	409.70
	Density	1.0±0.1 g/cm3	Boiling Point	503.4±38.0 °C at 760 mmHg
	Molecular Formula	C₂₇H₃₉D₇O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	211.8±21.4 °C

Use of 7α-Hydroxycholesterol-d7

7α-Hydroxycholesterol-d7 is the deuterium labeled 7α-Hydroxycholesterol. 7α-Hydroxycholesterol is a cholesterol oxide and is formed by both enzymatic and non-enzymatic oxidation. 7α-Hydroxycholesterol can be used as a biomarker for lipid peroxidation[1][2][3].

Name	7alpha-hydroxycholesterol-25,26,26,26,27,27,27-d7
Synonym	More Synonyms

Description	7α-Hydroxycholesterol-d7 is the deuterium labeled 7α-Hydroxycholesterol. 7α-Hydroxycholesterol is a cholesterol oxide and is formed by both enzymatic and non-enzymatic oxidation. 7α-Hydroxycholesterol can be used as a biomarker for lipid peroxidation[1][2][3].
Related Catalog	Signaling Pathways >> Others >> Others
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [2]. Ferderbar S, et al. Cholesterol oxides as biomarkers of oxidative stress in type 1 and type 2 diabetes mellitus. Diabetes Metab Res Rev. 2007 Jan;23(1):35-42. [3]. Kitano S, et al. Oxidative status of human low density lipoprotein isolated by anion-exchange high-performance liquid chromatography--assessment by total hydroxyoctadecadienoic acid, 7-hydroxycholesterol, and 8-iso-prostaglandin F(2alpha). Anal Chim Acta. 2007 Feb 28;585(1):86-93.

Density	1.0±0.1 g/cm3
Boiling Point	503.4±38.0 °C at 760 mmHg
Molecular Formula	C₂₇H₃₉D₇O₂
Molecular Weight	409.70
Flash Point	211.8±21.4 °C
Exact Mass	388.334137
PSA	40.46000
LogP	7.41
Vapour Pressure	0.0±2.9 mmHg at 25°C
Index of Refraction	1.539
Storage condition	20°C

(3S,7S,8S,9S,10R,13R,14S,17R)-10,13-Dimethyl-17-[(2R)-5-methyl-2-hexanyl]-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-3,7-diol (non-preferred name)

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: cholest-5-en-3?,7α-diol-d7
Price: Negotiable
Purity: 99.0%
Delivery: 10 Day
Contact: Huang
Email: sales@echemcloud.com

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7α-Hydroxycholesterol-d7

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