4-(5-Formyl-thiazol-2-yl)-piperazine-1-carboxylic acid tert-butyl ester

Modify Date: 2024-01-19 17:21:04

4-(5-Formyl-thiazol-2-yl)-piperazine-1-carboxylic acid tert-butyl ester Structure
4-(5-Formyl-thiazol-2-yl)-piperazine-1-carboxylic acid tert-butyl ester structure
Common Name 4-(5-Formyl-thiazol-2-yl)-piperazine-1-carboxylic acid tert-butyl ester
CAS Number 354587-77-2 Molecular Weight 297.37300
Density 1.269g/cm3 Boiling Point 437.7ºC at 760 mmHg
Molecular Formula C13H19N3O3S Melting Point N/A
MSDS N/A Flash Point 218.5ºC

 Names

Name tert-butyl 4-(5-formyl-1,3-thiazol-2-yl)piperazine-1-carboxylate

 Chemical & Physical Properties

Density 1.269g/cm3
Boiling Point 437.7ºC at 760 mmHg
Molecular Formula C13H19N3O3S
Molecular Weight 297.37300
Flash Point 218.5ºC
Exact Mass 297.11500
PSA 90.98000
LogP 2.01560
Index of Refraction 1.58

 Safety Information

HS Code 2934100090

 Synthetic Route

~39%

4-(5-Formyl-thiazol-2-yl)-piperazine-1-carboxylic acid tert-butyl ester Structure

4-(5-Formyl-thi...

CAS#:354587-77-2

Literature: F. HOFFMANN-LA ROCHE AG Patent: WO2006/72436 A1, 2006 ; Location in patent: Page/Page column 71 ;

~89%

4-(5-Formyl-thiazol-2-yl)-piperazine-1-carboxylic acid tert-butyl ester Structure

4-(5-Formyl-thi...

CAS#:354587-77-2

Literature: Anandan, Sampath-Kumar; Ward, John S.; Brokx, Richard D.; Denny, Trisha; Bray, Mark R.; Patel, Dinesh V.; Xiao, Xiao-Yi Bioorganic and Medicinal Chemistry Letters, 2007 , vol. 17, # 21 p. 5995 - 5999

 Precursor & DownStream

Precursor  2

DownStream  0

 Customs

HS Code 2934100090
Summary 2934100090 other compounds containing an unfused thiazole ring (whether or not hydrogenated) in the structure VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%