MurA-IN-1

Modify Date: 2024-01-02 18:03:31

MurA-IN-1 Structure
MurA-IN-1 structure
Common Name MurA-IN-1
CAS Number 354815-90-0 Molecular Weight 215.25
Density 1.25g/cm3 Boiling Point 406.5ºC at 760 mmHg
Molecular Formula C13H13NO2 Melting Point N/A
MSDS USA Flash Point 199.7ºC
Symbol GHS06
GHS06
Signal Word Danger

 Use of MurA-IN-1


MurA-IN-1 (compound 1a) is a PTPRR inhibitor, with IC50 values of 0.23 μM, 0.8 μM, 0.75 μM and 0.09 μM for PTP1B, PTPN5, PTPN7 and PTPRR, respectively[1]. (A family of human MAPK-specific protein tyrosine phosphatases)

 Names

Name 3a,4,5,9b-tetrahydro-3h-cyclopenta[c]quinoline-4-carboxylic acid

 MurA-IN-1 Biological Activity

Description MurA-IN-1 (compound 1a) is a PTPRR inhibitor, with IC50 values of 0.23 μM, 0.8 μM, 0.75 μM and 0.09 μM for PTP1B, PTPN5, PTPN7 and PTPRR, respectively[1]. (A family of human MAPK-specific protein tyrosine phosphatases)
Related Catalog
Target

IC50: 0.23 μM (PTP1B), 0.8 μM (PTPN5), 0.75 μM (PTPN7), 0.09 μM (PTPRR)[1].

References

[1]. Jeyanthy Eswaran, et al. Crystal structures and inhibitor identification for PTPN5, PTPRR and PTPN7: a family of human MAPK-specific protein tyrosine phosphatases. Biochem J. 2006 May 1;395(3):483-91.

 Chemical & Physical Properties

Density 1.25g/cm3
Boiling Point 406.5ºC at 760 mmHg
Molecular Formula C13H13NO2
Molecular Weight 215.25
Flash Point 199.7ºC
Exact Mass 215.09500
PSA 49.33000
LogP 2.36300
Index of Refraction 1.606

 Safety Information

Symbol GHS06
GHS06
Signal Word Danger
Hazard Statements H301
Precautionary Statements P301 + P310
Hazard Codes Xi
RIDADR UN 2811 6.1 / PGIII
HS Code 2933990090

 Customs

HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
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Price: ¥500/100 mg

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