SIBA structure
|
Common Name | SIBA | ||
---|---|---|---|---|
CAS Number | 35899-54-8 | Molecular Weight | 339.41300 | |
Density | N/A | Boiling Point | N/A | |
Molecular Formula | C14H21N5O3S | Melting Point | N/A | |
MSDS | N/A | Flash Point | N/A |
Use of SIBASIBA selectively inhibits spermine synthase, IC50=8 uM.IC50 value: 8 uMTarget: spermine synthaseSIBA is a powerful antiproliferative drug. SIBA has been reported to inhibit cell transformation induced by oncogenic RNA or DNA viruses, the growth of transformed mouse mammary cells, the mitogen-stimulated blastogenesis of lymphocytes and the capping of herpes virus mRNA 161. It has also been demonstrated that an antimalarial activity is exerted by SIBA against Plasmodium falciparum in cultures. |
Name | 5'-Isobutylthioadenosine |
---|---|
Synonym | More Synonyms |
Description | SIBA selectively inhibits spermine synthase, IC50=8 uM.IC50 value: 8 uMTarget: spermine synthaseSIBA is a powerful antiproliferative drug. SIBA has been reported to inhibit cell transformation induced by oncogenic RNA or DNA viruses, the growth of transformed mouse mammary cells, the mitogen-stimulated blastogenesis of lymphocytes and the capping of herpes virus mRNA 161. It has also been demonstrated that an antimalarial activity is exerted by SIBA against Plasmodium falciparum in cultures. |
---|---|
Related Catalog | |
References |
Molecular Formula | C14H21N5O3S |
---|---|
Molecular Weight | 339.41300 |
Exact Mass | 339.13700 |
PSA | 144.61000 |
LogP | 0.99810 |
Storage condition | 2-8℃ |
HS Code | 2934999090 |
---|
HS Code | 2934999090 |
---|---|
Summary | 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
adenosine,5'-s-(2-methylpropyl)-5'-thio- |
5-isobutylthio-5-deoxyadenosine |
SIBA |