4-Piperidone, 1-hydroxy-2,2,6,6-tetramethyl-

Modify Date: 2024-01-03 19:51:05

4-Piperidone, 1-hydroxy-2,2,6,6-tetramethyl- Structure
4-Piperidone, 1-hydroxy-2,2,6,6-tetramethyl- structure
Common Name 4-Piperidone, 1-hydroxy-2,2,6,6-tetramethyl-
CAS Number 3637-11-4 Molecular Weight 171.23700
Density 1.02g/cm3 Boiling Point 257.5ºC at 760mmHg
Molecular Formula C9H17NO2 Melting Point N/A
MSDS N/A Flash Point 109.5ºC

 Use of 4-Piperidone, 1-hydroxy-2,2,6,6-tetramethyl-


Tempone-H may be used as a spin trap in chemical and biological systems to quantify peroxynitrite and superoxide radical formation. Ferric and cupric ions are effective oxidants of Tempone-H[1][2].

 Names

Name 1-hydroxy-2,2,6,6-tetramethylpiperidin-4-one
Synonym More Synonyms

  Biological Activity

Description Tempone-H may be used as a spin trap in chemical and biological systems to quantify peroxynitrite and superoxide radical formation. Ferric and cupric ions are effective oxidants of Tempone-H[1][2].
Related Catalog
In Vitro Using TEMPONE-H the obtained sensitivity in the detection of peroxynitrite or superoxide radicals is about 10-fold higher than using the spin traps DMPO or TMIO[1].
References

[1]. Dikalov S, et al. Quantification of peroxynitrite, superoxide, and peroxyl radicals by a new spin trap hydroxylamine 1-hydroxy-2,2,6,6-tetramethyl-4-oxo-piperidine. Biochem Biophys Res Commun. 1997 Jan 3;230(1):54-7.

[2]. Dikalov SI, et al. Amyloid beta peptides do not form peptide-derived free radicals spontaneously, but can enhance metal-catalyzed oxidation of hydroxylamines to nitroxides. J Biol Chem. 1999 Apr 2;274(14):9392-9.

 Chemical & Physical Properties

Density 1.02g/cm3
Boiling Point 257.5ºC at 760mmHg
Molecular Formula C9H17NO2
Molecular Weight 171.23700
Flash Point 109.5ºC
Exact Mass 171.12600
PSA 40.54000
LogP 1.53560
Storage condition -20°C

 Safety Information

HS Code 2933399090

 Synthetic Route

 Customs

HS Code 2933399090
Summary 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

1-hydroxy-2,2,6,6-tetramethyl-piperidin-4-one
1-Hydroxy-2,2,6,6-tetramethyl-4-oxopiperidine
4-oxo-TEMPO-H
4-Piperidinone,1-hydroxy-2,2,6,6-tetramethyl
1-Hydroxy-2,2,6,6-tetramethyl-piperidin-4-on
2,2,6,6-tetramethyl-4-oxo-1-piperidinyloxy
Tempone-H
N-hydroxy-4-oxo-2,2,6,6-tetramethylpiperidine
1-Hydroxy-2,2,6,6-tetramethyl-4-piperidinone
Top Suppliers:I want be here

Get all suppliers and price by the below link:

4-Piperidone, 1-hydroxy-2,2,6,6-tetramethyl- suppliers

4-Piperidone, 1-hydroxy-2,2,6,6-tetramethyl- price

Related Compounds: More...
4-Ethylsulfonyl-1-hydroxy-2,2,6,6-tetramethyl-1,2,5,6-tetrahydropyridin
67042-08-4
(4-carboxy-1-hydroxy-2,2,6,6-tetramethyl-4-piperidyl)azanide; cobalt(+2) cation
42724-75-4
(4-carboxy-1-hydroxy-2,2,6,6-tetramethyl-4-piperidyl)azanide; platinum(+2) cation
42735-79-5
4-[chloro-[(1-hydroxy-2,2,6,6-tetramethyl-4-piperidyl)oxy]phosphoryl]oxy-1-hydroxy-2,2,6,6-tetramethyl-piperidine
43143-25-5
(4-carboxy-1-hydroxy-2,2,6,6-tetramethyl-4-piperidyl)azanide; nickel(+2) cation
42724-76-5
4-Piperidinol,1-hydroxy-2,2,6,6-tetramethyl-, 4,4',4''-phosphorothioate (9CI)
64566-89-8
4-Piperidinol,1-hydroxy-2,2,6,6-tetramethyl-, 4,4',4''-phosphate (9CI)
64566-88-7
4-[chloromethyl-[(1-hydroxy-2,2,6,6-tetramethyl-4-piperidyl)oxy]phosphoryl]oxy-1-hydroxy-2,2,6,6-tetramethyl-piperidine
52814-00-3
4-diphenoxyphosphoryloxy-1-hydroxy-2,2,6,6-tetramethyl-piperidine
52814-02-5
2-(4-(ethylthio)phenyl)-N-(7-methylbenzo[1,2-d:3,4-d']bis(thiazole)-2-yl)acetamide
919865-78-4
4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
1158522-08-7
N-(4-bromophenyl)-2-({1-[(cyclopentylcarbamoyl)methyl]-5-(hydroxymethyl)-1H-imidazol-2-yl}sulfanyl)acetamide
923150-67-8
1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
940364-43-2
2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
134104-43-1
1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
131615-57-1
(4-Methyl-tetrahydro-furan-2-yl)-methanol
6906-52-1
N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
930439-75-1
4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
1018584-77-4
tert-Butyl-DL-alanine
1375289-11-4