Sm4

Modify Date: 2024-04-04 08:24:16

Sm4 Structure
Sm4 structure
Common Name Sm4
CAS Number 365542-77-4 Molecular Weight 292.32900
Density 1.3±0.1 g/cm3 Boiling Point 481.4±33.0 °C at 760 mmHg
Molecular Formula C19H16O3 Melting Point N/A
MSDS N/A Flash Point 259.1±21.9 °C

 Use of Sm4


Sm4 is a SOX18 inhibitor. Sm4 shows SOX18-DNA binding inhibitory activity. Sm4 selectively affects SOX18 transcriptional output in vitro. Sm4 blocks SoxF transcriptional activity in vivo. Sm4 can be used for cancer metastasis and vascular cancers research[1].

 Names

Name 2-Hydroxy-6-[2-(2-naphthyl)ethyl]benzoic acid
Synonym More Synonyms

 Sm4 Biological Activity

Description Sm4 is a SOX18 inhibitor. Sm4 shows SOX18-DNA binding inhibitory activity. Sm4 selectively affects SOX18 transcriptional output in vitro. Sm4 blocks SoxF transcriptional activity in vivo. Sm4 can be used for cancer metastasis and vascular cancers research[1].
Related Catalog
References

[1]. Mathias FRANCOIS. Inhibitors of sox18 protein activity for treating angiogenesis- and/or lymphangiogenesis-related diseases. Patent, WO2018112545A1.

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 481.4±33.0 °C at 760 mmHg
Molecular Formula C19H16O3
Molecular Weight 292.32900
Flash Point 259.1±21.9 °C
Exact Mass 292.11000
PSA 57.53000
LogP 5.77
Vapour Pressure 0.0±1.3 mmHg at 25°C
Index of Refraction 1.688

 Synonyms

2-Hydroxy-6-[2-(2-naphthyl)ethyl]benzoic acid
Benzoic acid, 2-hydroxy-6-[2-(2-naphthalenyl)ethyl]-