silybin (mixture of silybin a and silybin b)

Modify Date: 2024-01-05 15:55:35

silybin (mixture of silybin a and silybin b) structure	Common Name	silybin (mixture of silybin a and silybin b)
	CAS Number	36804-17-8	Molecular Weight	482.44
	Density	1.527g/cm3	Boiling Point	793ºC at 760 mmHg
	Molecular Formula	C₂₅H₂₂O₁₀	Melting Point	160ºC
	MSDS	N/A	Flash Point	274.4ºC

Use of silybin (mixture of silybin a and silybin b)

(±)-Silybin is the racemate of Silybin (HY-N0779A). Silybin induces apoptosis and exhibits hepatoprotective, antioxidant, anti-inflammatory, anti-cancer activity[1][2].

Name	(2R,3R)-3,5,7-trihydroxy-2-[3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-2,3-dihydro-1,4-benzodioxin-6-yl]-2,3-dihydrochromen-4-one
Synonym	More Synonyms

Description	(±)-Silybin is the racemate of Silybin (HY-N0779A). Silybin induces apoptosis and exhibits hepatoprotective, antioxidant, anti-inflammatory, anti-cancer activity[1][2].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
References	[1]. Silvia Zappavigna, et al. Silybin-Induced Apoptosis Occurs in Parallel to the Increase of Ceramides Synthesis and miRNAs Secretion in Human Hepatocarcinoma Cells. Int J Mol Sci. 2019 May 3;20(9):2190. [2]. Runbin Sun, et al. Silybin ameliorates hepatic lipid accumulation and modulates global metabolism in an NAFLD mouse model. Biomed Pharmacother. 2020 Mar;123:109721.

Description

(±)-Silybin is the racemate of Silybin (HY-N0779A). Silybin induces apoptosis and exhibits hepatoprotective, antioxidant, anti-inflammatory, anti-cancer activity[1][2].

Related Catalog

Research Areas >> Cancer

Signaling Pathways >> Others >> Others

References

[1]. Silvia Zappavigna, et al. Silybin-Induced Apoptosis Occurs in Parallel to the Increase of Ceramides Synthesis and miRNAs Secretion in Human Hepatocarcinoma Cells. Int J Mol Sci. 2019 May 3;20(9):2190.

[2]. Runbin Sun, et al. Silybin ameliorates hepatic lipid accumulation and modulates global metabolism in an NAFLD mouse model. Biomed Pharmacother. 2020 Mar;123:109721.

Density	1.527g/cm3
Boiling Point	793ºC at 760 mmHg
Melting Point	160ºC
Molecular Formula	C₂₅H₂₂O₁₀
Molecular Weight	482.44
Flash Point	274.4ºC
Exact Mass	481.11300
PSA	159.05000
LogP	3.38430
Index of Refraction	1.684
Storage condition	Freezer