Chlorhexidine Dihydrochloride

Modify Date: 2024-01-02 12:17:08

Chlorhexidine Dihydrochloride Structure
Chlorhexidine Dihydrochloride structure
Common Name Chlorhexidine Dihydrochloride
CAS Number 3697-42-5 Molecular Weight 578.369
Density N/A Boiling Point 699.3ºC at 760mmHg
Molecular Formula C22H32Cl4N10 Melting Point 255-262 ºC
MSDS Chinese USA Flash Point 376.7ºC

 Use of Chlorhexidine Dihydrochloride


Chlorhexidine dihydrochloride is an antibacterial, used as an antiseptic and for other applications.

 Names

Name Chlorhexidine dihydrochloride
Synonym More Synonyms

 Chlorhexidine Dihydrochloride Biological Activity

Description Chlorhexidine dihydrochloride is an antibacterial, used as an antiseptic and for other applications.
Related Catalog

 Chemical & Physical Properties

Boiling Point 699.3ºC at 760mmHg
Melting Point 255-262 ºC
Molecular Formula C22H32Cl4N10
Molecular Weight 578.369
Flash Point 376.7ºC
Exact Mass 576.156555
PSA 167.58000
LogP 7.88780
Storage condition 2-8°C
Water Solubility 0.06 g/100 mL (20 ºC)

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
XA5285000
CHEMICAL NAME :
2,4,11,13-Tetraazatetradecanediimidamide, N,N''-bis(4-chlorophenyl)-3,12-diimino-, dihydrochloride
CAS REGISTRY NUMBER :
3697-42-5
LAST UPDATED :
199303
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C22-H30-Cl2-N10.2Cl-H
MOLECULAR WEIGHT :
578.44

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>5 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
BJPCAL British Journal of Pharmacology and Chemotherapy. (London, UK) V.1-33, 1946-68. For publisher information, see BJPCBM. Volume(issue)/page/year: 9,192,1954 *** U.S. STANDARDS AND REGULATIONS *** EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year: 54,7740,1989

 Safety Information

Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi:Irritant
Risk Phrases R36/37/38
Safety Phrases 53-45-61-36-26
RIDADR UN 2811 6.1/PG 1
WGK Germany 3
RTECS MA4375000
Packaging Group III
Hazard Class 9

 Articles84

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Evaluation of preventive programs in high caries active preschool children.

Swed. Dent. J. 37(1) , 23-9, (2013)

Although caries prevalence in preschool children has dramatically decreased during the last decades it is still a large problem for a minor group of these children. Great efforts have been invested in...

Effect of irrigation with Tetraclean on bacterial leakage of obturated root canals.

N. Y. State Dent. J. 80(3) , 39-43, (2014)

The purpose of the study presented here was to evaluate the effect of Tetraclean, Hypoclean, Chlor-XTRA, 2% chlorhexidine and 6% sodium hypochlorite/17% EDTA as a final irrigant on bacterial leakage o...

Short-term decline in all-cause acquired infections with the routine use of a decontamination regimen combining topical polymyxin, tobramycin, and amphotericin B with mupirocin and chlorhexidine in the ICU: a single-center experience.

Crit. Care Med. 42(5) , 1121-30, (2014)

In a multicenter, placebo-controlled, randomized, double-blind trial, we showed that acquired infections in intubated patients were reduced by the combination of topical polymyxin plus tobramycin and ...

 Synonyms

1,1'-Hexamethylenebis[5-(4-chlorophenyl)biguanide] Dihydrochloride
Chlorhexidine HCl
1,6-Bis(N5-[p-chlorophenyl]-N1-biguanido)hexane
N,N''''-Hexane-1,6-diylbis[N'-(4-chlorophenyl)(imidodicarbonimidic diamide)] dihydrochloride
(1E)-2-[6-[[amino-[(E)-[amino-(4-chloroanilino)methylidene]amino]methylidene]amino]hexyl]-1-[amino-(4-chloroanilino)methylidene]guanidine,dihydrochloride
N,N''''-1,6-Hexanediylbis[N'-(4-chlorophenyl)(imidodicarbonimidic diamide)] dihydrochloride
Chlorhexidine Dihydrochloride
Chlorhexidine hydrochloride
1,1’-Hexamethylenebis(5-[p-chlorophenyl]biguanide)
Chlorhexidine 2HCl
EINECS 200-636-0
UNII-E64XL9U38K
Imidodicarbonimidic diamide, N,N''''-1,6-hexanediylbis[N'-(4-chlorophenyl)-, hydrochloride (1:2)
MFCD00068998
Chlorhexidine (dihydrochloride)
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