STAT6-IN-3

Modify Date: 2024-01-12 22:20:53

STAT6-IN-3 structure	Common Name	STAT6-IN-3
	CAS Number	371919-80-1	Molecular Weight	731.51
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₃₂H₃₅IN₃O₇P	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of STAT6-IN-3

STAT6-IN-3 (Compound 18a) is a STAT6 inhibitor (IC50= 44 nM). STAT6-IN-3 targets the Src Homology 2 (SH2) domain of STAT6. STAT6-IN-3 can be used for research of inflammation such as asthma[1].

Name	STAT6-IN-3

Description	STAT6-IN-3 (Compound 18a) is a STAT6 inhibitor (IC50= 44 nM). STAT6-IN-3 targets the Src Homology 2 (SH2) domain of STAT6. STAT6-IN-3 can be used for research of inflammation such as asthma[1].
Related Catalog	Signaling Pathways >> Stem Cell/Wnt >> STAT Signaling Pathways >> JAK/STAT Signaling >> STAT Research Areas >> Inflammation/Immunology
References	[1]. Mandal PK, et al. Targeting the Src Homology 2 (SH2) Domain of Signal Transducer and Activator of Transcription 6 (STAT6) with Cell-Permeable, Phosphatase-Stable Phosphopeptide Mimics Potently Inhibits Tyr641 Phosphorylation and Transcriptional Activity. J Med Chem. 2015 Nov 25;58(22):8970-84.

Molecular Formula	C₃₂H₃₅IN₃O₇P
Molecular Weight	731.51