Amidefrine

Modify Date: 2024-01-13 18:06:20

Amidefrine Structure
Amidefrine structure
Common Name Amidefrine
CAS Number 37571-84-9 Molecular Weight 244.31100
Density N/A Boiling Point N/A
Molecular Formula C10H16N2O3S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Amidefrine


Amidephrine is a selective agonist of alpha 1-adrenoceptor. Amidephrine inhibits inhibits monopulse field contraction of the vas deferens epithelium and prostate gland[1].

 Names

Name (+/-)-Amidephrine
Synonym More Synonyms

 Amidefrine Biological Activity

Description Amidephrine is a selective agonist of alpha 1-adrenoceptor. Amidephrine inhibits inhibits monopulse field contraction of the vas deferens epithelium and prostate gland[1].
Related Catalog
Target

α1-adrenergic receptor

In Vitro Amidephrine (10-100 nM) 在年轻成年大鼠和老年大鼠输精管的上皮和前列腺中,剂量依赖性地抑制单脉冲场收缩,EC50 分别为 6.79-6.48 μM 和 6.17-6.18 μM[1]。
References

[1]. Docherty JR, et al. An examination of age-related changes in pre- and postsynaptic alpha-adrenoceptors in the rat isolated vas deferens. Eur J Pharmacol. 1983 Nov 25;95(3-4):171-6.  

 Chemical & Physical Properties

Molecular Formula C10H16N2O3S
Molecular Weight 244.31100
Exact Mass 244.08800
PSA 86.81000
LogP 1.85560

 Synonyms

Amidephrine